A Brief History of Lithium Treatment in Psychiatry

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The history of lithium as a psychiatric medication is marked by its serendipitous discovery, its lengthy path to US Food and Drug Administration approval, and controversy surrounding its current status in bipolar disorder treatment. Without doubt, the discovery of lithium as a psychotropic agent forever changed the course of psychiatry. The drug’s fascinating, and sometimes contentious, history is reviewed here.

Prim Care Companion CNS Disord 2017;19(5):17br02140