Psychiatric and Somatic Markers of Anxiety: Identification and Pharmacologic Treatment
Alan J. Gelenberg, MD
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Anxiety disorders are widely prevalent but insufficiently
recognized and inadequately treated in primary care practice. The
annual costs of morbidity and mortality of these disorders
approach $50 billion, substantially more than costs for
schizophrenia or all affective disorders combined. Somatization
of anxiety contributes to the challenges of making an accurate
diagnosis and to the indirect costs associated with delaying
appropriate treatment. Pharmacologic interventions give
clinicians the necessary tools to treat anxiety safely and
effectively. Former therapeutic choices were limited to
benzodiazepines, buspirone, and older antidepressants, but newer
anxiolytic agents have become available. The selective serotonin
reuptake inhibitors and agents with dual reuptake inhibition,
such as venlafaxine XR, are optimizing therapy and yielding less
risk for serious adverse events, greater safety in long-term
therapy, and opportunity for improved patient compliance. These
newer antidepressants provide substantial efficacy in patients
with comorbid anxiety and depression, commonly seen in the
primary care setting.
Prim Care Companion J Clin Psychiatry 2000;2(2):49-54
https://doi.org/10.4088/PCC.v02n0204
© Copyright 2000 Physicians Postgraduate Press, Inc.
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