Original Research
Original Research
Lipid-Related Polygenic Effects Across the AD Spectrum
September 21, 2021
Lipid-related genes and serum lipids may affect cognitive function via regulating brain networks. This study investigated polygenic effects of the lipid metabolic pathway on cerebrospinal fluid core biomarkers, cognition,...
Original Research
Long-Acting Injectable Antipsychotic Plus Customized Adherence Enhancement
September 16, 2021
Medication adherence is often difficult in bipolar patients. This trial combined a behavioral customized adherence enhancement approach with long-acting injectable antipsychotics and assessed effects on adherence, symptoms, and functional...
Original Research
Predictors of Early-Onset vs Adult-Onset Psychosis
September 14, 2021
Most research on first-episode psychosis has focused on adults. This study aimed to explore differences in early-life characteristics of patients with early-onset versus those with adult-onset psychotic disorders and...
Original Research
Coaggregation of BD-I/BD-II With Major Psychiatric Disorders
September 7, 2021
Etiologic differences between bipolar I and II disorders have been challenged recently. This study used a large nationwide database to determine the risk of familial aggregation of specific psychiatric...
Original Research
Equine-Assisted Therapy for PTSD in Veterans
August 31, 2021
Veterans have high rates of posttraumatic stress disorder (PTSD) and historically poor treatment outcomes and high attrition. This study assessed the feasibility, acceptability, and outcomes of equine-assisted therapy for...
Original Research
Mindfulness-Based Therapy for Suicide Prevention
August 31, 2021
A search is ongoing for treatments that reduce suicide attempts, especially for veterans. This study evaluated if Mindfulness-Based Cognitive Therapy for Preventing Suicide Behavior effectively augmented treatment-as-usual enhanced for...
Original Research
Efficacy and Safety of AR19 in Adults With ADHD
August 24, 2021
Misuse of stimulant medications prescribed for attention-deficit/hyperactivity disorder (ADHD) can have adverse medical outcomes. This study tested the safety and efficacy of AR19, a manipulation-resistant formulation of amphetamine, in...
Original Research
Cost Burden of Depression and Suicide on Caregivers
August 12, 2021
Do caregivers of patients with major depressive disorder (MDD) and suicidal ideation and/or suicide attempts have significantly greater direct and indirect costs compared to MDD-alone and non-MDD caregivers? Read...
Original Research
Inflammation and Cognition in ECT-Treated Older Adults
August 10, 2021
Patients and practitioners often avoid electroconvulsive therapy (ECT) due to the risk of cognitive side effects. This study assessed whether inflammatory markers before ECT are associated with cognitive functioning...
