Original Research

JCP
Original Research

October 31, 2017

Which medication do you choose first when treating anxiety in children? This study used a large commercial claims database to determine which antianxiety medications clinicians are selecting as first-line...
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JCP
Original Research

October 25, 2017

Most studies to date have focused on the effects of mood stabilizers in bipolar I patients. This postmarketing surveillance study examines whether lamotrigine better prevents episodes in those with...
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JCP
Original Research

October 24, 2017

Does rate of adherence to antidepressants vary much between physicians? This study of electronic health records and insurance claims data investigates the question, as well as whether adherence to...
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JCP
Original Research

October 24, 2017

Therapeutic drug monitoring during clozapine therapy can be inconvenient as well as uncomfortable for patients. This study tested a novel method of dried blood spot (finger prick) monitoring as...
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JCP
Original Research

October 24, 2017

Do second-generation antidepressants pose an increased risk of seizure? These authors used Taiwan's national health insurance database to investigate the question, including whether dose or medication class affects the...
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JCP
Original Research

October 17, 2017

Cognitive dysfunction in bipolar disorder is a strong predictor of disability, poor quality of life, and longer time to recovery. Could cognitive remediation, a behavioral intervention used successfully in...
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JCP
Original Research

October 17, 2017

Placebo effects are a common obstacle in the search for Alzheimer's disease treatments. This analysis of data from the large CATIE-AD study investigates ways to screen out potential placebo...
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JCP
Original Research

October 17, 2017

Total prescription stimulant sales for adults have now surpassed those for youth, and targeting the misuse of these medications is important in order to reduce health and social consequences....
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JCP
Original Research

October 10, 2017

Although anosognosia—or impaired illness awareness—is common in Alzheimer's disease, it occurs less frequently in mild cognitive impairment. Read this article to learn if anosognosia in patients with mild cognitive...
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JCP
Original Research

October 3, 2017

Identification of physiologic biomarker precursors that result from prolonged psychological stress allows for possible prevention of negative outcomes; however, long-term data on the association of trauma with such biomarkers...
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JCP
Original Research

September 26, 2017

When clinicians use methadone as the standard treatment for opioid-dependent pregnant women, must they be concerned about its effects on the heart of mother and child? Read this study...
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JCP
Original Research

September 26, 2017

Is it possible to predict which patients taking SSRIs are most likely to suffer a stroke? This study identifies the period of time after SSRI initiation during which strokes...
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JCP
Original Research

September 19, 2017

Injectable antipsychotics can help address the problem of nonadherence, which can lead to relapse. This study looks at the efficacy of the injectable antipsychotic aripiprazole lauroxil in achieving and...
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JCP
Original Research

September 12, 2017

Cognitive impairment often limits the ability of patients with schizophrenia to function in the community, but no medications are approved to treat this impairment. Read this article to learn...
JCP
Original Research

September 12, 2017

In patients with bipolar I disorder, chronotherapeutics combined with lithium has a lower risk than traditional antidepressants of inducing manic switches. Learn from this study the 5 immune-regulatory compounds...
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JCP
Original Research

September 5, 2017

Read this article to learn whether borderline personality disorder and bipolar disorder are 2 different disorders or manifestations of the same disorder.
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JCP
Original Research

August 29, 2017

Autism has been linked to higher rates of depression and to suicidality. This study leveraged data from a large insurance database to find out whether the presence of depression...
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JCP
Original Research

August 23, 2017

When it comes to using smartphones, how much is too much? This study compared the ability of clinical interview versus app-recorded data to establish a diagnosis of smartphone addiction. ...
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JCP
Original Research

August 23, 2017

When children as young as 3 years old are prescribed anticonvulsants, antipsychotics, or psychotropic polypharmacy for their first diagnosis of ADHD, what is the trajectory of treatment in subsequent...
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JCP
Original Research

August 23, 2017

What are the primary causes of poor patient outcomes in psychiatry, and what can be done to address these? A panel of 58 experts in psychiatry completed a survey...
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JCP
Original Research

August 23, 2017

The past decades have seen a surge in stimulant prescriptions for ADHD—is this treatment causing long-term functional changes to the brain? This observational study from The Netherlands looked at...
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JCP
Original Research

August 23, 2017

In the US, young adults have historically had lower rates of health coverage than other groups. The dependent coverage provision of the Affordable Care Act extended private health insurance...
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JCP
Original Research

August 23, 2017

Although exposure therapies are effective for PTSD, they require many sessions, and some patients still have residual symptoms. Methylene blue, an agent that enhances memory, has previously shown success...
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JCP
Original Research

August 23, 2017

About half of OCD patients treated with an adequate trial of serotonin reuptake inhibitors (SRIs) fail to fully respond to treatment. This randomized controlled trial examined whether N-acetylcysteine, a...
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