Steve Seiner, MD

Psychiatric Neurotherapeutics Program, McLean Hospital, Belmont, Massachusetts; Department of Psychiatry, Harvard Medical School, Boston, Massachusetts

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About

Steve Seiner, MD, is affiliated with the Psychiatric Neurotherapeutics Program at McLean Hospital and the Department of Psychiatry at Harvard Medical School. Seiner has published on treatment-resistant depression, specifically comparing repeated ketamine infusion and intranasal esketamine. The work appears in Psychiatrist.com and involves collaboration with co-authors including Amanda Sedgewick and Brian Boyle.

Publications

JCP
Comparative Effects of Repeated Ketamine Infusion vs Intranasal Esketamine in Patients with Treatment Resistant Depression: A Retrospective Chart Review
Original Research

Comparative Effects of Repeated Ketamine Infusion vs Intranasal Esketamine in Patients with Treatment Resistant Depression: A Retrospective Chart Review

September 22, 2025

In this naturalistic sample of patients with similarly severe treatment resistant depression treated over a 4- to 5-week induction period, intravenous racemic ketamine was associated with more rapid response...
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