Vladimir Maletic, MD

Original Research

Adjunctive Cariprazine for Anxiety Symptoms in MDD

April 30, 2025

Cariprazine added to antidepressant therapy reduced anxiety symptoms in patients with and without anxiety at baseline.

Original Research

Esmethadone in Patients With Major Depressive Disorder and Inadequate Response to Standard Antidepressants

June 17, 2024

Although this trial of esmethadone did not meet its primary outcome, some secondary and post hoc outcomes were promising.

Narrative Review

L-Methylfolate as Adjunctive Therapy in MDD Treatment

May 9, 2023

l-Methylfolate is effective as an adjunctive treatment in MDD and may especially benefit patients with higher body mass index and inflammation.

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Original Research

Screening for Bipolar Disorder and Evaluating the RMS

April 25, 2023

Health care providers found the Rapid Mood Screener, a new bipolar I disorder screening tool, to be superior to the widely used Mood Disorder Questionnaire in sensitivity/specificity, brevity, practicality,...