Wei-Chen Lin, MD, PhD

JCP
Appetite Hormone Regulation Biotypes of Major Affective Disorders
Original Research

April 9, 2025

Three appetite hormone regulation biotypes were identified among patients with major affective disorders. They were associated with proinflammatory cytokine profiles and executive function, with one biotype group showing poorer...
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JCP
Effects of Low-Dose Ketamine Infusion on Hopelessness and Suicidal Thoughts
Original Research

July 8, 2024

A single infusion of low-dose ketamine resulted in a brief (~4 hour) yet significant reduction in hopelessness.
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JCP
Excess Mortality Associated With Schizophrenia
Original Research

September 13, 2023

Females, patients with connective tissue disorders, and those aged 20 years or younger were especially impacted by the effect of schizophrenia on increasing mortality.
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JCP
Original Research

May 11, 2021

Case reports suggest a link between obsessive-compulsive disorder (OCD) and dementia, but this association has received little research. The current study investigated dementia risk among OCD patients using a...
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JCP
Original Research

November 10, 2020

Can we determine which patients will respond to ketamine just by observing their mood during the infusion? This study evaluated antidepressant outcomes with ketamine in 71 patients, focusing on ...
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JCP
Original Research

September 10, 2019

Should a pregnant woman take acetaminophen? Learn the specific trimesters when consumption places the child most at risk for later being diagnosed with ADHD and whether other factors, like...
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JCP
Article

March 12, 2019

What are some risk factors for (and protective factors against) sexually transmitted infections among adolescents and young adults with bipolar disorder?
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JCP
Original Research

March 5, 2019

Do kids who take second-generation antipsychotics have the same risk of developing type 2 diabetes as adults taking these drugs? In this longitudinal follow-up study of over 91,000 adolescents...
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JCP
Original Research

May 1, 2018

Anecdotal evidence suggests that risk factors related to type 2 diabetes mellitus—including obesity, hypertension, and dyslipidemia—may be associated with attention-deficit/hyperactivity disorder. This study looked at this possible relationship more...
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JCP
Original Research

December 19, 2017

Up to 50% of patients with systemic inflammation from ongoing physical illness develop major depressive disorder. This nationwide, population-based study in 2 independent cohorts explored the relationship between inflammation...
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JCP
Original Research

August 29, 2017

Autism has been linked to higher rates of depression and to suicidality. This study leveraged data from a large insurance database to find out whether the presence of depression...
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