Bipolar Disorder, characterized by mood swings from manic highs to depressive lows, is a complex psychiatric condition that requires nuanced understanding and care. The Journal of Clinical Psychiatry offers in-depth insights into bipolar disorder, from diagnostic challenges to evidence-based treatment strategies. Our expert editors ensure that content is comprehensive, relevant, and cutting-edge, providing psychiatrists with the tools they need to offer holistic care to those living with this challenging condition.
Bipolar Disorder
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Recently published articles about Bipolar Disorder
Original Research
Safety and Efficacy of Maintenance Treatment with Aripiprazole Once-Monthly in Black/African American Adults With Bipolar I Disorder
March 9, 2026
The safety and efficacy of AOM 400 were comparable between Black/African American and non-Black/African American patients with bipolar I disorder
Original Research
Outcomes and Practice Patterns of LAI Versus Oral Antipsychotics Among Patients With Bipolar I Disorder in the US
March 2, 2026
Long-acting injectable antipsychotics, especially second-generation formulations, are associated with reduced rehospitalization in bipolar I disorder compared to oral antipsychotics.
Case Report
Oral Glutamatergic Modulation with Dextromethorphan and Piracetam for Refractory Bipolar Disorder With OCD
February 23, 2026
Three patients with combined bipolar disorder and OCD experienced remission of depressive, anxious, and obsessive-compulsive symptoms after piracetam was added to dextromethorphan.
Original Research
Triple Network Model–Based Functional Dysconnectivity in Young People With Major Affective Disorders With or Without Suicidal Ideation
November 19, 2025
In young people with major affective disorders, suicidality is associated with extensive functional dysconnectivity in the triple networks (default mode network, salience network, and frontoparietal network).