Bipolar Disorder, characterized by mood swings from manic highs to depressive lows, is a complex psychiatric condition that requires nuanced understanding and care. The Journal of Clinical Psychiatry offers in-depth insights into bipolar disorder, from diagnostic challenges to evidence-based treatment strategies. Our expert editors ensure that content is comprehensive, relevant, and cutting-edge, providing psychiatrists with the tools they need to offer holistic care to those living with this challenging condition.
Bipolar Disorder
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Recently published articles about Bipolar Disorder
Original Research
Neurocognition and Impulsivity in Veterans with Bipolar Spectrum Disorders: Suicide Attempters Versus Nonattempters
October 29, 2025
Poorer working memory is associated with suicide attempt independent of depression, while verbal learning impairments associated with suicide attempt may be influenced by depression.
Commentary
Beyond the Boxed Warning: A Call for Regulation of Psychiatry’s Most Teratogenic Drug
October 6, 2025
The authors assert that while valproate remains invaluable for certain severe conditions, the high risk of teratogenicity means stringent safeguards are needed to regulate its use by individuals capable...
Original Research
Effects of Interpersonal and Social Rhythm Therapy on Suicidal Ideation in Adults with Bipolar II Depression
September 29, 2025
There was no significant difference in suicidal ideation in those receiving IPSRT plus placebo vs IPSRT plus quetiapine. IPSRT has the potential to mitigate suicidal ideation in patients with...
Academic Highlights
Clinical Application of Aripiprazole Monohydrate Long-Acting Injectables for the Treatment of Bipolar Type I Disorder: A Consensus Panel Report
August 13, 2025
A consensus panel reviews treatment considerations in the use of long-acting injectable aripiprazole monohydrate in bipolar type I disorder.
Original Research
Klotho and Matrix Metalloproteinase-9 Levels and Their Association with Inhibitory Dyscontrol in Adolescents with First-Episode Major Affective Disorders
July 16, 2025
Adolescents with bipolar disorder and those with MDD had significantly lower Klotho levels compared with the control group; those with bipolar disorder had the highest MMP-9 levels, followed by...
