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Combining Clozapine and Xanomeline/Trospium Chloride: Mechanisms of Action and the Genesis of Catatonia
September 25, 2026
Warren Cheng, MD Candidate, on a case where abruptly stopping clozapine while continuing Cobenfy (xanomeline-trospium) preceded severe catatonia, and the rebound-cholinergic hypothesis that may explain the risk as Cobenfy...