Commentary
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Commentary
Precision Medicine for Suicide Prevention: It’s Time to Take the Next Step
December 22, 2025
The authors recommend moving toward a precision medicine approach to suicide prevention that considers the person, their circumstances and biology, treatment delivery context, and conditions that contribute to the...
Commentary
Beyond the Boxed Warning: A Call for Regulation of Psychiatry’s Most Teratogenic Drug
October 6, 2025
The authors assert that while valproate remains invaluable for certain severe conditions, the high risk of teratogenicity means stringent safeguards are needed to regulate its use by individuals capable...
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Commentary
Lower Risk of Cardiovascular Disorders in Antidepressant-Treated Women Veterans: Encouraging Findings but Concerns Remain
May 7, 2025
Comments on a study by Sumner et al that followed 609,546 women veterans for a mean of 8.8 years to look at associations of antidepressants with incident CVD.
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Featured Commentary Research
Original Research
Comparing Risk Prediction for Suicide Attempts and Deaths After Emergency Department Visits
March 4, 2026
Distinct factors predict nonfatal and fatal suicidal events. Male sex and depression are the strongest predictors for fatal events; being under 65 years of age and suicidal ideation are...
Commentary
Prioritizing Mental Health to Optimize Perinatal, Fetal, and Neonatal Outcomes
September 24, 2025
Following an FDA panel discussion on use of SSRIs in pregnancy, the authors highlight the need for balanced conversations and shared decision-making accounting for the risks of untreated disease...
Commentary
Practitioners Providing Care for Persons with Severe Mental Disorders Should Routinely Screen for Metabolic Dysfunction–Associated Steatotic Liver Disease
September 10, 2025
Persons with severe mental illnesses should be routinely screened for MASLD as part of a psychiatric and medical assessment that includes social and economic determinants of health, risk factors...