Major Depressive Disorder (MDD) is a debilitating condition characterized by persistent feelings of sadness, hopelessness, and a lack of interest in daily activities. Understanding its underlying causes and effective treatments is crucial for patient well-being. The Journal of Clinical Psychiatry provides a comprehensive look into MDD, offering evidence-based therapeutic approaches and the latest research findings. Our expert editors ensure content is relevant and actionable, aiding psychiatrists in offering holistic care to those grappling with depression.
Depression and Major Depressive Disorder
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Recently published articles about Depression (MDD)
Original Research
Race, Ethnicity, Socioeconomic Status, Clinical Characteristics, and Postpartum Depression in Patients with a History of Depressive Episodes
June 17, 2026
Patients who were non-White and had lower incomes had higher PPD risk. Higher antidepressant dosing before pregnancy, stopping antidepressants during pregnancy, and moderate-severe symptoms early in pregnancy were associated...
Original Research
CBT following Esketamine for Major Depression and Suicidal Ideation for Relapse Prevention: The CBT-ENDURE Randomized Trial
May 4, 2026
In patients with major depression and suicidal ideation, adding a 16-week CBT course to esketamine led to greater improvements in suicidal ideation and depression severity than esketamine alone.
Clinical and Practical Psychopharmacology
Association of SSRIs and Other Antidepressants With Dental Implant Failure
March 18, 2026
Antidepressant users should be educated about the risk of dental implant failure, and efforts should be made to identify and negate other risk factors for implant failure.
