Diary From the Front Lines
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Case Series
Esketamine Augmented With Dextromethorphan/Bupropion for Treatment Resistant Depression: A Case Series
November 3, 2025
Three patients with TRD who had no or partial response to esketamine monotherapy as part of a clinical trial received augmentation with dextromethorphan/bupropion 45 mg/105 mg daily.
Recent PCC Articles on Diary From the Front Lines
Case Report
Cerebrotendinous Xanthomatosis: Unraveling Prominent Neuropsychiatric Symptoms and Mild Cognitive Impairment With Subsequent Clinical Improvement
October 30, 2025
A 51-year-old woman who exhibited an 8-month history of significant cognitive decline and behavioral changes, including forgetfulness, irritability, and anger outbursts, leading to an initial diagnosis of mild neurocognitive...
