This work may not be copied, distributed, displayed, published, reproduced, transmitted, modified, posted, sold, licensed, or used for commercial purposes. By downloading this file, you are agreeing to the publisher’s Terms & Conditions.

Original Articles

Medication Compliance Among Patients With Bipolar Disorder and Substance Use Disorder

Roger D. Weiss, Shelly F. Greenfield, Lisa M. Najavits, Jose A. Soto, Dana Wyner, Mauricio Tohen, and Margaret L. Griffin

Published: April 15, 1998

Article Abstract

Background: This study examined patterns ofmedication compliance and reasons for noncompliance amongpatients with bipolar disorder and substance use disorder.

Method: Forty-four patients with current bipolardisorder and substance use disorder were administered astructured interview regarding lifetime compliance withprescribed psychotropic medications.

Results: Patients who were prescribed bothlithium and valproate were significantly (p=.03) more likely toreport full compliance with valproate than with lithium. Sideeffects were the most common reason for lithium noncompliance,but were not cited as a reason for valproate noncompliance. Also,a common pattern of noncompliance among patients prescribedbenzodiazepines, neuroleptics, and tricyclic antidepressants wasthe use of more medication than prescribed.

Conclusion: Valproate may have greateracceptability than lithium among patients with bipolar disorderand substance use disorder. Clinicians should also be aware thatthese patients may take higher doses of medication thanprescribed.

Volume: 59

Quick Links: Bipolar Disorder

Continue Reading…

Subscribe to read the entire article

$40.00

Buy this Article as a PDF

Sign-up to stay
up-to-date today!

SUBSCRIBE

Already registered? Sign In

Case Report

Safety and Tolerability of Concomitant Intranasal Esketamine Treatment With Irreversible, Nonselective MAOIs: A Case Series

Three cases suggest that concomitant use of intranasal esketamine with an irreversible, nonselective MAOI is safe in...

Read More...