Electroconvulsive Therapy Decreases Dopamine D2 Receptor Binding in the Anterior Cingulate in Patients With Depression: A Controlled Study Using Positron Emission Tomography With Radioligand [11C]FLB 457

Article Abstract

Results: There were no significant differences in D2 receptor binding between patients with MDD and controls. All 7 patients showed clinical improvements in response to ECT treatment (P‘ ‰<‘ ‰.001). Significant changes in D2 receptor binding, a mean of 25.2% reduction, were found in the right rostral anterior cingulate (AC) following ECT (P‘ ‰<‘ ‰.001).

Volume: 71

Quick Links: Depression (MDD) , Electroconvulsive Therapy

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