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Educational Activity

Why Is Mechanism of Action Important in Antidepressant Treatment?

Thomas L. Schwartz, MD

Published: May 25, 2016

Article Abstract

Antidepressants are one of the most common treatment strategies for patients diagnosed with major depressive disorder (MDD). However, antidepressant medications have different mechanisms of action that can theoretically and in practice affect how patients respond. Clinicians should assess their patients’ symptoms and response to medication at every visit to determine whether or not the treatment is fully effective. Here, follow the case of Maria, a 42-year-old teacher who is experiencing her first depressive episode.

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Find more articles on this and other psychiatry and CNS topics:
The Journal of Clinical Psychiatry
The Primary Care Companion for CNS Disorders


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