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More JCP Articles
Original Research
Comparative Effects of Repeated Ketamine Infusion vs Intranasal Esketamine in Patients with Treatment Resistant Depression: A Retrospective Chart Review
September 22, 2025
In this naturalistic sample of patients with similarly severe treatment resistant depression treated over a 4- to 5-week induction period, intravenous racemic ketamine was associated with more rapid response…
Original Research
Relationships between Prenatal Body Composition and Mental Health Are Moderated by Physical Activity and Diet
September 15, 2025
Higher body fat mass during pregnancy is associated with more depression and anxiety symptoms. However, physical activity and adherence to high-quality diets can lessen these effects.
Clinical and Practical Psychopharmacology
Ketamine-Associated Uropathy During Therapeutic and Nontherapeutic Use
September 10, 2025
Higher doses, more frequent dosing, longer treatment duration, and oral administration are potential risk factors for ketamine-associated uropathy in maintenance therapy.
Commentary
Practitioners Providing Care for Persons with Severe Mental Disorders Should Routinely Screen for Metabolic Dysfunction–Associated Steatotic Liver Disease
September 10, 2025
Persons with severe mental illnesses should be routinely screened for MASLD as part of a psychiatric and medical assessment that includes social and economic determinants of health, risk factors…
Insights
It Takes Guts to Be Mentally Ill, Part 1: A Brief Overview of the Human Gut Microbiota
September 8, 2025
Dr. Henry Nasrallah introduces the human gut microbiota and its role in brain health, highlighting how early life, diet, antibiotics, and lifestyle impact microbial balance — and how gut…
Insights
It Takes Guts to Be Mentally Ill, Part 2: The Relationship Between the Gut Microbiota and Psychosis
September 8, 2025
Dr. Henry Nasrallah examines how gut microbiota imbalances—aka “leaky gut”—are linked to psychiatric conditions like depression, anxiety, and psychosis, and explores how diet, probiotics, and microbiome therapies may improve…
Brief Report
Nonmedical Use and Substance Use Disorder Symptoms in US Adults Co-Prescribed Opioids and Benzodiazepines
September 8, 2025
While most adults with co-use reported no nonmedical use (NMU), they demonstrated increased odds of NMU and substance use disorder symptoms relative to those prescribed opioids only, benzodiazepines only,…
