Empowering mental health professionals with peer-reviewed psychiatric research and insights
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More JCP Articles
Case Series
Esketamine Augmented With Dextromethorphan/Bupropion for Treatment Resistant Depression: A Case Series
November 3, 2025
Three patients with TRD who had no or partial response to esketamine monotherapy as part of a clinical trial received augmentation with dextromethorphan/bupropion 45 mg/105 mg daily.
Original Research
Neurocognition and Impulsivity in Veterans with Bipolar Spectrum Disorders: Suicide Attempters Versus Nonattempters
October 29, 2025
Poorer working memory is associated with suicide attempt independent of depression, while verbal learning impairments associated with suicide attempt may be influenced by depression.
Original Research
Brief Video Intervention to Increase Treatment-Seeking Intentions in Young Adults
October 27, 2025
This brief video intervention was associated with greater increases in treatment-seeking intentions in people with self-reported psychiatric symptoms who were not previously engaged in the mental healthcare system and…
Original Research
Autoimmune Diseases, Treatments, and Dementia Risk: A Population-Based Case-Control Study from Taiwan
October 15, 2025
Thirteen autoimmune diseases were linked with an elevated dementia risk, particularly Behçet’s disease, multiple sclerosis, and lupus. Associations with vascular dementia were stronger than with Alzheimer’s disease.
Original Research
Brexpiprazole for the Treatment of Co-Occurring Schizophrenia and Substance Use Disorder
October 13, 2025
This pilot trial suggests that brexpiprazole might be beneficial in reducing substance craving and use and improve quality of life in this difficult-to-treat patient population.
Brief Report
Treatment with (Es)ketamine in Catatonia: A Systematic Review of Case Reports
October 13, 2025
Recent evidence suggests that NMDA receptor antagonists, such as ketamine, may offer benefit in catatonia. This systematic review was conducted to evaluate the efficacy and safety of ketamine and…
