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Clinical Psychiatry

Empowering mental health professionals with peer-reviewed psychiatric research and insights

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Functional Outcomes of an Antipsychotic in Schizophrenia: Generalizable or Specific Effect?
Commentary

Functional Outcomes of an Antipsychotic in Schizophrenia: Generalizable or Specific Effect?

March 1, 2022

This commentary takes a closer look at Correll and colleagues’ findings on functional outcomes with brexpiprazole.
JCP
Postpartum Harm Thoughts and Maternal Aggression
Original Research

Postpartum Harm Thoughts and Maternal Aggression

March 1, 2022

Many new mothers have unwanted intrusive thoughts of infant-related harm, and such thoughts are a core feature of obsessive-compulsive disorder (OCD). This study explores whether unwanted intrusive thoughts and…
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JCP
Measurement-Based Care for Psychotic Disorders
Original Research

Measurement-Based Care for Psychotic Disorders

March 1, 2022

Measurement-based care (MBC) can improve patient outcomes, but data on its use in psychosis are sparse. This study examined the use of patient-reported outcome measures in veterans with psychosis…
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JCP
Effects of Brexpiprazole on Functioning in Schizophrenia
Original Research

Effects of Brexpiprazole on Functioning in Schizophrenia

March 1, 2022

Drawing on 4 RCTs and 2 open-label extension studies of brexpiprazole, this analysis looks at the effects of this medication on functioning both in the short term and over…
, , , et al
JCP
PTSD in US Military Veterans
Original Research

PTSD in US Military Veterans

February 22, 2022

This study sought to determine the likelihood of developing posttraumatic stress disorder (PTSD) after direct versus indirect exposures and examined the effects of direct and indirect PTE exposure and…
, , , et al
JCP
Psychological Dimensions of Palliative Care Consultation
Cross Talk: Case Conferences From MGH

Psychological Dimensions of Palliative Care Consultation

February 22, 2022

This compelling case presentation illustrates the challenges of providing palliative care during the pandemic. The expert discussion that follows examines the case from various perspectives and suggests ways clinicians…
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JCP
TAAR1 Educational Resource Video
Insights

TAAR1 Educational Resource Video

February 17, 2022

See a short video explaining how trace amine–associated receptor 1 (TAAR1) affects neurotransmitters in the brain.
JCP
Emerging Treatments in Schizophrenia Video
Insights

Emerging Treatments in Schizophrenia Video

February 17, 2022

In this video, 3 experts discuss the challenge of treating schizophrenia with the current medications, which target blockade of dopaminergic receptors, and explore 4 new medications (ulotaront, KarXT, CVL-231,…
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JCP
Neuropsychiatric Symptoms of Autoimmune Encephalitis
Narrative Review

Neuropsychiatric Symptoms of Autoimmune Encephalitis

February 15, 2022

This review and case series of 7 patients highlights the variable presentations of autoimmune encephalitis in order to help physicians better recognize it in patients with mixed neuropsychiatric symptoms.
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JCP
Exclusion and Refusal in Youth Suicide Prevention RCTs
Meta-Analysis

Exclusion and Refusal in Youth Suicide Prevention RCTs

February 15, 2022

Ineligibility for and refusal to take part in randomized controlled trials (RCTs) can make samples unrepresentative and limit generalizability of findings. This meta-analysis estimated the exclusion and refusal rates…
, , , et al
JCP
Emerging Treatments in Schizophrenia
InfoPack

Emerging Treatments in Schizophrenia

February 15, 2022

Experts discuss the brain circuits involved in schizophrenia, the current medications, and new agents in phase 3 trials that do not directly block postsynaptic D2 receptors. Phase 2 data…
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JCP
Mental Health Outcomes in an Area With a Higher vs Lower COVID-19 Incidence
Original Research

Mental Health Outcomes in an Area With a Higher vs Lower COVID-19 Incidence

February 8, 2022

This comparison of subjects from 2 areas of Italy investigated whether living in an area with a greater rate of COVID-19 infection impacted outcomes in patients with anxiety and…
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