Letter to the Editor

Item 9 of the Patient Health Questionnaire (PHQ-9) is a robust predictor of suicide attempt and suicide death. However, it still has a substantial false-negative rate. This study of...

Use of selective serotonin reuptake inhibitors in clinical practice has increased. Early presentation of serotonin syndrome can be vague and easily dismissed. The authors of this report describe a...

Benzodiazepine tolerance after multiple days or weeks has been described—but not within 48 hours. Read this report of a man with catatonia who rapidly developed tolerance to lorazepam in...

Oseltamivir (Tamiflu) is widely used for the treatment of influenza. However, adverse neuropsychiatric effects, including behavioral changes and perceptional disturbance, have been observed in oseltamivir-treated patients. Here, read about...

Hypomanic and manic symptoms are common in the postpartum period and can occur alone or in combination with symptoms of depression. Here, case histories are presented of 2 women...

It is important to highlight the significance of pharmacodynamics and pharmacokinetics in drug interactions. These interactions affect drug plasma concentrations and must be considered when a patient is taking...