Letter to the Editor

Recently published articles about Letter to the Editor

PCC
Psychopharmacotherapy Updates
Letter to the Editor

April 7, 2026

The authors provide an update for busy prescribers on the latest FDA-approved psychotropic medications.
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JCP
Metformin for Prevention of Antipsychotic-Induced Weight Gain: The Optimal Strategy
Letter to the Editor

April 6, 2026

Dr Huang discusses the potential for B12 deficiency in patients coprescribed antipsychotics and metformin.
JCP
Vitamin B12 Deficiency Risk With Metformin for Weight Management in Second-Generation Antipsychotic Recipients: Reply to Mulsant et al
Letter to the Editor

March 18, 2026

Daggolu and Chen reply to a letter commenting on their study of metformin use in patients receiving second-generation antipsychotics.
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JCP
Concurrent Metformin and Second-Generation Antipsychotics: The Need to Add Vitamin B12
Letter to the Editor

March 18, 2026

The authors recommend vigilance for potential B12 deficiency when coprescribing metformin and antipsychotics.
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JCP
Neural Dysconnectivity and Affective Disorders: Integrating Sleep and Emotional Regulation Perspectives
Letter to the Editor

March 16, 2026

The authors discuss sleep disturbance in the context of recent research on functional dysconnectivity in the brain’s triple networks.
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JCP
Triple Network Dysconnectivity and Sleep Disturbance in Young People With Suicidal Ideation: Reply to Ferruzzi et al
Letter to the Editor

March 16, 2026

Cheng et al reply to a letter regarding their recent study of triple network functional dysconnectivity in major affective disorders.
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Recent JCP Articles on Letter to the Editor

JCP
The Position of Clozapine in Patients with Treatment-Resistant Schizophrenia: Reply to Mattes
Letter to the Editor

January 28, 2026

Dr Andrade replies to a letter about his article on factors affecting choice of clozapine versus other antipsychotics.
JCP
Urological Commentary on Ketamine-Associated Uropathy
Letter to the Editor

January 26, 2026

The author comments on a recent article reviewing ketamine-associated uropathy in therapeutic and nontherapeutic settings.
JCP
Ketamine-Associated Uropathy in Therapeutic Contexts: Reply to Abdelrahman
Letter to the Editor

January 26, 2026

Dr Andrade responds to a letter commenting on his recent review of ketamine-associated uropathy in therapeutic and nontherapeutic settings.

Recent PCC Articles on Letter to the Editor

PCC
Kratom-Induced Psychosis
Letter to the Editor

January 8, 2026

The author comments on the complexity of substance-induced presentations, particularly those related to newly available psychoactive substances such as kratom.
PCC
Semaglutide for Alcohol Use Disorder
Letter to the Editor

January 1, 2026

The authors explore potential mechanisms underlying the relationship between GLP-1 agonists and AUD as well as studies evaluating semaglutide for AUD.
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PCC
Psychosis Screening in Genetic Disorders
Letter to the Editor

December 4, 2025

The author discusses routine monitoring for the development of psychotic symptoms among individuals with rare genetic disorders that confer risk for psychosis.

Featured Letter to the Editor Research

PCC
Lithium in Mood and Bipolar Disorders
Narrative Review

April 16, 2026

Long-term lithium treatment is associated with a meaningful reduction in suicide attempts and deaths, an advantage that is important to discuss with patients and families at elevated suicide risk.
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PCC
Cultural Manifestations of Bereavement in a Chinese American Patient
Case Report

April 16, 2026

The authors highlight the difficulties of applying western psychiatric concepts to cultural minorities, as seen in a case of complicated bereavement in a 54-year-old Chinese American woman.
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JCP
Phase 2b Study to Evaluate Basmisanil as Adjunctive Treatment in Patients With Cognitive Impairment Associated With Schizophrenia
Original Research

April 15, 2026

Although basmisanil did not improve cognitive deficits, the results offer insight into factors that should facilitate design of more informative trials.
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PCC
Psychosis and Kratom
Letter to the Editor

March 10, 2026

The authors discuss the possible association between psychosis and kratom use.
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PCC
CTRA, Stress, and Yoga
Letter to the Editor

February 24, 2026

The authors examine the historical context of stress, the neurobiological mechanisms of conserved transcriptional response to adversity and stress, and how yoga practices counteract its effects.
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PCC
Psychotropic-Related Aspiration Hazards
Letter to the Editor

February 10, 2026

The authors discuss the importance of a choking prevention policy to identify those at heightened risk for choking hazards, particularly psychiatric patients.
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PCC
Lysing Catatonia to Uncover the Driving Illness
Letter to the Editor

January 29, 2026

The author comments on a recent PCC article and offers an alternative diagnostic perspective.
PCC
Clarifying the Delirium in Bell’s Mania: Reply to Intrator
Letter to the Editor

January 29, 2026

The authors respond to a letter to the editor commenting on their article.
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JCP
Rationale for Clozapine Trial
Letter to the Editor

January 28, 2026

Dr Mattes comments on a recent article examining the use of clozapine versus other antipsychotic options.

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