Original Research

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Recently published articles about Original Research

JCP
Pilot Study of High Frequency TMS for Bipolar Depression
Original Research

May 20, 2024

In this study of patients with bipolar depression, 87.1% reached response and 74.2% reached remission with 6 weeks of rTMS.
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JCP
Clinical Index to Discriminate Between MCI and Mild Dementia
Original Research

May 20, 2024

A combined index from the MMSE and Lawton Index performed well in discriminating between Clinical Dementia Rating scores of 0.5 and 1.
, , , et al
JCP
Clozapine Exposure and Risk of Hematologic Malignancies in Veterans with Schizophrenia
Original Research

May 15, 2024

Clozapine exposure of at least 5 years was associated with hematologic malignancy, and the increased risk was dose-dependent.
, , , et al
JCP
Effects of a Multicomponent Intervention for Older Adults at Risk of Dementia
Original Research

May 13, 2024

This randomized controlled trial of cognitive training plus lifestyle guidance demonstrated improved cognitive function in community-dwelling older adults at risk of dementia.
, , , et al
JCP
Effect of Time From Onset of MDD on Response to Esmethadone
Original Research

May 13, 2024

Esmethadone 25 and 50 mg were more effective in reducing depression scale scores in patients who had a shorter time since their first major depressive episode.
, , , et al
JCP
Barriers to Esketamine Nasal Spray Use in Treatment-Resistant Depression
Original Research

May 6, 2024

Potential barriers to treatment with esketamine nasal spray include travel distance, insurance, low socioeconomic status, and minority communities.
, , , et al
PCC
Psychotropic Medication Prescriptions for Oncology Patients
Original Research

May 2, 2024

In palliative home care, psychotropic medications are frequently prescribed by palliative doctors primarily for symptom management, with limited psychiatric consultations and challenges in accessing psychological evaluations.
, , , et al
JCP
Concomitant LAIs and Time to Rehospitalization in Patients Receiving Clozapine
Original Research

May 1, 2024

Clozapine plus LAI antipsychotics was associated with lower risk of rehospitalization compared to both clozapine plus oral antipsychotics and clozapine monotherapy.
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JCP
Clozapine Use and Specific Indications
Original Research

April 29, 2024

Clozapine initiation is uncommon in people with psychotic disorders who have experienced events suggesting clozapine is indicated, with even lower rates in Black and Hispanic patients.
, , , et al
JCP
Antisuicidal Effects of Ketamine in Patients With Comorbid AUD
Original Research

April 24, 2024

Intranasal ketamine induced rapid antidepressant effects versus placebo but did not significantly change suicidal ideation scores in patients with alcohol use disorder and suicidal ideation with past attempt.
, , , et al
JCP
Fully Remote Trial of tACS for Treatment of MDD
Original Research

April 22, 2024

Rapid improvement in depression was associated with tACS, particularly for women. Patients can use tACS treatment on their own at home, and it is associated with minimal adverse events.
, , , et al
PCC
Mindfulness, Problematic Social Media Use, and Anxiety
Original Research

April 16, 2024

Use of trait mindfulness–based interventions may help reduce anxiety levels in students who present with severe problematic social media use.
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Consensus Report on XT Use in Practice

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Figure: Graphic promoting Consensus Report on Xanomeline-Trospium; colorful net design shown with JCP logo in lower left.

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