Original Research

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Recently published articles about Original Research

JCP
Original Research

February 27, 2018

Although electroconvulsive therapy is the most robust acute treatment for MDD, nearly one-third of patients don' t respond to it—but why? This study investigated C-reactive protein and interleukin-6, both...
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JCP
Original Research

February 27, 2018

Even though methylphenidate is the most commonly prescribed medication for ADHD, not all ADHD patients respond to this agent equally. Can sluggish cognitive tempo—sluggishness, sleepiness, and/or "daydreaminess"—affect methylphenidate response?...
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JCP
Original Research

February 27, 2018

Clinical heterogeneity is a key challenge to understanding suicidal risk, as different pathways to suicidal behavior exist. Discover the latent classes of late-life depression in this longitudinal study examining...
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JCP
Original Research

February 20, 2018

Read why treatment resistant depression, even compared to MDD, poses a significant direct and indirect cost burden to US employers and employment status.
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JCP
Original Research

February 20, 2018

Youth who are at risk for relapse of MDD may benefit from treatment strategies aimed at preventing the return of symptoms. This study looked at clinical characteristics associated with...
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JCP
Original Research

February 20, 2018

People at risk of Alzheimer's disease often have higher functional connectivity in several brain networks. Does this functional connectivity change over time—and is there a pattern of change specific...
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JCP
Original Research

February 13, 2018

Because recent research supports the effectiveness of antipsychotics in nonresponsive major depressive disorder, examining national prescribing trends for these drugs in MDD is a timely topic. Using data from...
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JCP
Original Research

February 13, 2018

Adventurous and explosive temperament profiles have been associated with antisocial and borderline personality disorders. This analysis of over 2,000 participants in the Young Finns study looks at whether these...
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JCP
Original Research

February 6, 2018

Clinicians often have little direction regarding optimal treatment options for obsessive-compulsive disorder (OCD). Read this article to learn the relative effectiveness of 7 strategies for treating OCD.
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JCP
Original Research

January 23, 2018

The Maudsley Staging Method has been validated as a way to quantify and predict depression course and outcome, but its generalizability to a community-based population had not yet been...
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JCP
Original Research

January 16, 2018

Early behavioral variant frontotemporal dementia (bvFTD) is often mistaken for major depressive disorder. Could patients' processing of facial emotions provide clues to differentiate the two? In this study, patients...
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JCP
Original Research

January 9, 2018

The self-report Concise Associated Symptoms Tracking Scale (CAST-SR) was designed to track symptoms such as mania and anxiety in depressed outpatients being treated with antidepressants. This study used data...
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Consensus Report on XT Use in Practice

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Figure: Graphic promoting Consensus Report on Xanomeline-Trospium; colorful net design shown with JCP logo in lower left.

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