Case Report March 5, 2020

A Case of Serotonin Syndrome in the Setting of Dextromethorphan-Based Cough Medicine, Tramadol, and Multiple Antidepressants

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Prim Care Companion CNS Disord 2020;22(2):19l02518

Article Abstract

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Serotonin syndrome is a potentially life-threatening condition that is particularly relevant to both primary care and psychiatric clinical practice. Serotonin syndrome has been documented with increasing frequency in recent years, in part due to the increased use of selective serotonin reuptake inhibitors, serotonin-norepinephrine reuptake inhibitors, and other serotonergic medications. However, it is still relatively underdiagnosed and underreported.