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Psychiatric Briefs

Primary Care Companion J Clin Psychiatry 2000;2(6):230-232

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Objective: The authors hypothesized that the development of borderline disorder is associated with traumatic events that occur early in patients’ lives and loss events experienced by the mothers of patients around the time of the patients’ birth. Method: Sixty-six patients with DSM-III-R borderline personality disorder and 146 controls with psychiatric illnesses other than borderline personality disorder or dissociative disorder were compared in a case-control study. A multivariate logistic regression model was produced to remove the confounding effect of patient age, family size, and inpatient versus outpatient status as well as the possible effects of the 2 variables of interest (patients’ traumatic experiences and losses experienced by the mother) on each other.​