This work may not be copied, distributed, displayed, published, reproduced, transmitted, modified, posted, sold, licensed, or used for commercial purposes. By downloading this file, you are agreeing to the publisher’s Terms & Conditions.


Enhancing Pharmacologic Effects in the Treatment of Depression in Women

Susan G. Kornstein, MD; and Geoffry McEnany, RN, PhD, CS

Published: September 30, 2000

Article Abstract

The prevalence of depressive disorders in women is twice that in men. This gender difference emerges around the time of puberty and persists through the childbearing years. Reproductive events and psychosocial factors are important influences on depression in women. Women often present with a typical depressive symptoms and comorbid disorders that can complicate both diagnosis and treatment. Sex differences in pharmacokinetics have been noted, as well as differences in antidepressant treatment response. While sleep disturbances, sexual dysfunction, and weight gain may be part of the constellation of depressive symptoms, they are also important considerations in selecting a treatment option for depressed women.

Some JCP and PCC articles are available in PDF format only. Please click the PDF link at the top of this page to access the full text.

Volume: 2

Quick Links: Depression (MDD)


Sign-up to stay
up-to-date today!


Already registered? Sign In

Original Research

Prevalence and Correlates of Obsessive-Compulsive Symptoms in Individuals With Schizophrenia, Schizoaffective Disorder, or Bipolar Disorder

Prevalence and correlates of obsessive-compulsive symptoms and OCD were identified from the case records of over 22,500...