Case Report June 5, 2025

Excited Catatonia in the Setting of Concurrent Opioid and Benzodiazepine Withdrawal

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Prim Care Companion CNS Disord 2025;27(3):25cr03927

  1. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision: DSM-5-TR. American Psychiatric Association Publishing; 2022.
  2. Burrow JP, Spurling BC, Marwaha R. Catatonia. In: StatPearls. StatPearls Publishing; 2024.
  3. Sayles BD, Royer EG, Meyer VM, et al. Malignant catatonia induced by concurrent opioid and benzodiazepine withdrawal. Prim Care Companion CNS Disord. 2023;25(2):22cr03346.
  4. Bush G, Fink M, Petrides G, et al. Catatonia. I. Rating scale and standardized examination. Acta Psychiatr Scand. 1996;93(2):129–136. CrossRef
  5. Fink M, Taylor MA. The catatonia syndrome: forgotten but not gone. Arch Gen Psychiatry. 2009;66(11):1173–1177.
  6. Lay S, Nguyen LL, Sangani A. Catatonia and opioid withdrawal: a case report. Cureus. 2024;16(3):e56396.
  7. Yeoh SY, Roberts E, Scott F, et al. Catatonic episodes related to substance use: a cross-sectional study using electronic healthcare records. J Dual Diagn. 2022;18(1):52–58. CrossRef
  8. Sandyk R. Endogenous opioid system in catatonia. Psychiatry Res. 1985;15(2):159. CrossRef
  9. Havemann U, Kuschinsky K. Neurochemical aspects of the opioid-induced “catatonia”. Neurochem Int. 1982;4(4):199–215. CrossRef