A Case of Delayed-Recovery Lithium-Induced Photophobia and Eye Irritation in a Patient With Bipolar I Disorder

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Lithium is one of the standard treatments for bipolar disorder, but it has a narrow therapeutic window and multiple side effects that may hinder adherence. Lithium has a wide profile of ophthalmic adverse effects including light accommodation impairment, xerophthalmia, extraocular muscle abnormalities, nystagmus, and ptosis.1 Photophobia was previously considered a rapidly reversible minor adverse effect of lithium mainly occurring in younger patients.