Letter to the Editor December 20, 2018

Oxcarbazepine-Induced Stevens-Johnson Syndrome

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Prim Care Companion CNS Disord 2018;20(6):18l02304

Article Abstract

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To the Editor: Stevens-Johnson syndrome (SJS) is a rare, potentially life-threatening hypersensitivity reaction involving the skin and mucous membranes.1,2 Medications associated with SJS have included anticonvulsants, particularly carbamazepine, lamotrigine, phenytoin, and valproate. Oxcarbazepine, an anticonvulsant structurally similar to carbamazepine, has been employed off-label to address affective instability in adult patients with bipolar disorder.