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Care Companionfor CNS Disorders

Advancing primary care with essential peer-reviewed research and insights into CNS disorders

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PCC
Valproate-Induced Hypermelanosis
Case Report

Valproate-Induced Hypermelanosis

September 30, 2025

The authors present 2 cases of hyperpigmentation induced by sodium valproate and valproic acid.
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PCC
Dexamethasone and Cyproheptadine Misuse
Case Report

Dexamethasone and Cyproheptadine Misuse

September 25, 2025

This case provides rare insight into the complications and delayed recognition associated with long-term, nonpsychoactive substance misuse, despite overt harm and a family history of addiction treatment.
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PCC
Neuropsychiatric Symptoms of Morquio Syndrome
Case Report

Neuropsychiatric Symptoms of Morquio Syndrome

September 25, 2025

A 70-year-old man with Morquio syndrome presented with mood instability and behavioral changes and became a significant nursing challenge.
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PCC
ECT for Auditory Hallucinations
Case Report

ECT for Auditory Hallucinations

September 23, 2025

A 19-year-old patient with Turner syndrome, schizophrenia and MDD presented for an ECT evaluation after multiple pharmacologic treatments failed to control her refractory auditory hallucinations, which had persisted for…
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PCC
Complicated Grief: Is There a Role for Naltrexone?
Letter to the Editor

Complicated Grief: Is There a Role for Naltrexone?

September 23, 2025

The authors discuss prolonged grief disorder and the use of medications like naltrexone as a potential treatment.
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PCC
Diagnosing and Treating Dizziness
Rounds in the General Hospital

Diagnosing and Treating Dizziness

September 18, 2025

Psychiatric treatment of dizziness includes behavioral therapy to decrease arousal to the identified stimulus and pharmacologic interventions to decrease acute anxiety and prevent onset of downstream anxiety.
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PCC
Imipramine-Induced Catatonia
Case Report

Imipramine-Induced Catatonia

September 18, 2025

The authors present the case of a 15-year-old girl with primary nocturnal enuresis and mild depressive symptoms, who later developed catatonia while on imipramine.
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PCC
Antihistamines: Indications, Interactions, and Adverse Effects
Rounds in the General Hospital

Antihistamines: Indications, Interactions, and Adverse Effects

September 16, 2025

Many antihistamines share a propensity for muscarinic receptor antagonism at higher doses, leading to symptoms of anticholinergic toxicity.
, , , et al
PCC
Amnesia Associated With Recreational Cannabis Use in an Adolescent
Case Report

Amnesia Associated With Recreational Cannabis Use in an Adolescent

September 16, 2025

A 17-year-old girl with no prior psychiatric or medical history presented to the psychiatry ED for confusion and agitation following recent cannabis use.
, , , et al
PCC
Knowledge of ECT for Catatonia
Letter to the Editor

Knowledge of ECT for Catatonia

September 11, 2025

The authors comment on a recent study by Kaur et al assessing what internists and neurologists know about catatonia.
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PCC
Mental Health Impact of COVID-19 Pandemic on the Mental Health of Middle-Aged and Older Adults: A Cross-sectional, Comparative Study
Original Research

Mental Health Impact of COVID-19 Pandemic on the Mental Health of Middle-Aged and Older Adults: A Cross-sectional, Comparative Study

September 11, 2025

Older adults were found to have less depression and anxiety compared to middle-aged adults; loneliness and perception of knowledge about COVID can affect the association between the presence of…
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PCC
Knowledge of Catatonia: Reply to Espinoza and Kellner
Letter to the Editor

Knowledge of Catatonia: Reply to Espinoza and Kellner

September 11, 2025

The authors reply to a letter to the editor commenting on their article.
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