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Care Companionfor CNS Disorders

Advancing primary care with essential peer-reviewed research and insights into CNS disorders

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JCP
Life After Clozapine: Managing Treatment-Resistant Schizophrenia When Clozapine Is No Longer an Option
ASCP Corner

March 11, 2026

The authors discuss treatment options and reinitiation of clozapine following clozapine discontinuation.
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JCP
Temporal Dynamics of Antidepressant Response Following Brexanolone Treatment in Postpartum Depression
Original Research

March 11, 2026

Temporal-Dynamics-Antidepressant-Response-Brexanolone-Treatment-Postpartum-Depression
, , , et al
The Sleep Disorder You Are Missing in Your Psychiatric Patients & The Modern Solution For It
news

March 11, 2026

Sleep disorders are frequently overlooked in psychiatric care. Explore why sleep screening matters and how home sleep testing improves diagnosis and treatment.
JCP
Behind the Manuscript: Inpatient Treatment of Suicidality with Brett Jones, MD, MSc, PhD, FRCPC
Podcast

March 10, 2026

Dr. Brett Jones reviews evidence-based interventions for inpatient suicidality: ketamine, chronotherapy, and dialectical behavior therapy for acute psychiatric care.
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JCP
Safety and Efficacy of Maintenance Treatment with Aripiprazole Once-Monthly in Black/African American Adults With Bipolar I Disorder
Original Research

March 9, 2026

The safety and efficacy of AOM 400 were comparable between Black/African American and non-Black/African American patients with bipolar I disorder
, , , et al
JCP
Efficacy of Olanzapine/Samidorphan on Negative Symptoms
Original Research

March 9, 2026

Olanzapine/samidorphan was associated with significant and durable improvement in negative symptoms of schizophrenia, overall and among patients with prominent and predominant negative symptoms.
, , , et al

Consensus Report on XT Use in Practice

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Figure: Graphic promoting Consensus Report on Xanomeline-Trospium; colorful net design shown with JCP logo in lower left.

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