This work may not be copied, distributed, displayed, published, reproduced, transmitted, modified, posted, sold, licensed, or used for commercial purposes. By downloading this file, you are agreeing to the publisher’s Terms & Conditions.

Original Articles

Psychiatric and Somatic Markers of Anxiety: Identification and Pharmacologic Treatment

Alan J. Gelenberg, MD

Published: April 1, 2000

Article Abstract

Anxiety disorders are widely prevalent but insufficiently recognized and inadequately treated in primary care practice. The annual costs of morbidity and mortality of these disorders approach $50 billion, substantially more than costs for schizophrenia or all affective disorders combined. Somatization of anxiety contributes to the challenges of making an accurate diagnosis and to the indirect costs associated with delaying appropriate treatment. Pharmacologic interventions give clinicians the necessary tools to treat anxiety safely and effectively. Former therapeutic choices were limited to benzodiazepines, buspirone, and older antidepressants, but newer anxiolytic agents have become available. The selective serotonin reuptake inhibitors and agents with dual reuptake inhibition, such as venlafaxine XR, are optimizing therapy and yielding less risk for serious adverse events, greater safety in long-term therapy, and opportunity for improved patient compliance. These newer antidepressants provide substantial efficacy in patients with comorbid anxiety and depression, commonly seen in the primary care setting.


Some JCP and PCC articles are available in PDF format only. Please click the PDF link at the top of this page to access the full text.

Related Articles

Volume: 2

Quick Links: Psychiatry

References

Sign-up to stay
up-to-date today!

SUBSCRIBE

Already registered? Sign In

Clinical and Practical Psychopharmacology

Antipsychotic Augmentation With N-Acetylcysteine for Patients With Schizophrenia

Dr Andrade discusses whether or not recent findings support the use of NAC as antipsychotic augmentation in...

Read More...