This work may not be copied, distributed, displayed, published, reproduced, transmitted, modified, posted, sold, licensed, or used for commercial purposes. By downloading this file, you are agreeing to the publisher’s Terms & Conditions.

Articles

Biology of Posttraumatic Stress Disorder

Rachel Yehuda, PhD

Published: April 30, 2000

Article Abstract

An understanding of the biological basis of posttraumatic stress disorder (PTSD) requires an examinationof the underlying neurobiology of fear and the factors that might contribute to an unsuccessfultermination of the fear response in some individuals. Several factors may lead to an inadequatetermination of a stress response, and the failure to contain the biological alterations initiated by stressmay have long-term adverse consequences. In particular, a prolonged continuation of biological responsesfollowing stress may lead to an inappropriate pairing of the traumatic memory with distressand may then initiate a cascade of secondary biological alterations. This article examines some of thebiological alterations in PTSD and develops a framework for understanding the development progressionof the neurobiology of this disorder.


Some JCP and PCC articles are available in PDF format only. Please click the PDF link at the top of this page to access the full text.

Volume: 2

Quick Links: PTSD , Trauma

References

Sign-up to stay
up-to-date today!

SUBSCRIBE

Already registered? Sign In

Insights

LAI Antipsychotics in Schizophrenia: Long-term Outcomes of Early Use

Using data from the...

Read More...