Systematic Review

Recently published articles about Systematic Review

PCC
NMDA Receptor Antagonists in Pediatric Autism
Systematic Review

NMDA Receptor Antagonists in Pediatric Autism

July 9, 2026

The authors review available data concerning the usage, efficacy, and side effects of memantine and amantadine, both NMDA receptor antagonists, in children with autism spectrum disorder.
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JCP
Thirty Years of the Diagnostic Criteria for Psychosomatic Research
Systematic Review

Thirty Years of the Diagnostic Criteria for Psychosomatic Research

March 25, 2026

Findings indicate that the DCPR are an essential integration to psychiatric taxonomy, particularly in the setting of medical disease, with prognostic and therapeutic implications.
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JCP
Rechallenge of Lamotrigine After Rash: A Systematic Review
Systematic Review

Rechallenge of Lamotrigine After Rash: A Systematic Review

December 31, 2025

Lamotrigine has been rechallenged safely in select cases, but it is critical to confirm that the initial rash did not have specific features of a severe rash in order...
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PCC
Psychiatric Adverse Effects of Hydroxychloroquine
Systematic Review

Psychiatric Adverse Effects of Hydroxychloroquine

May 29, 2025

Hydroxychloroquine use is associated with various neuropsychiatric adverse effects, cognitive impairments, and behavioral changes.
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PCC
Exercise and Fibromyalgia Pain
Systematic Review

Exercise and Fibromyalgia Pain

March 27, 2025

Adjunctive exercise therapies can be potentially beneficial in improving quality of life through reduction in pain catastrophizing.
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JCP
Inpatient Treatment of Suicidality
Systematic Review

Inpatient Treatment of Suicidality

January 8, 2025

Effective, rapid treatments that target suicidality in psychiatric inpatients are scarce in the existing literature and in clinical practice, underscoring the need for studies to identify and validate these...
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Recent JCP Articles on Systematic Review

JCP
Systematic Review of the Effects of Cannabis and Cannabinoids in PTSD Symptoms and Symptom Clusters
Systematic Review

Systematic Review of the Effects of Cannabis and Cannabinoids in PTSD Symptoms and Symptom Clusters

February 14, 2024

This review of 14 studies did not find major benefits of cannabinoids in improving overall PTSD symptoms, although some benefits in cluster B and E symptoms were seen. Risks...
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JCP
Predictors and Risk Factors of Treatment-Resistant Depression
Systematic Review

Predictors and Risk Factors of Treatment-Resistant Depression

November 13, 2023

Early identification of individuals with major depressive disorder who are likely to develop treatment-resistant depression (TRD) is needed. This study reviewed the literature to identify and categorize the predictors...
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JCP
Therapeutic Reference Range for Olanzapine
Systematic Review

Therapeutic Reference Range for Olanzapine

July 19, 2023

A therapeutic reference range of 20–40 ng/mL for oral and long-acting injectable olanzapine yields optimal treatment effects in schizophrenia spectrum disorders. Dose reduction is not needed above 40 ng/mL...
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Recent PCC Articles on Systematic Review

PCC
Therapist-Guided Versus Self-Guided CBT
Systematic Review

Therapist-Guided Versus Self-Guided CBT

March 21, 2024

Results were positive for the use of internet-based cognitive-behavioral therapy and encouraging for new methods of guided therapy and the inclusion of technology.
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PCC
Psychedelic Microdosing and Mental Health
Systematic Review

Psychedelic Microdosing and Mental Health

January 16, 2024

There is a growing body of evidence suggesting a positive correlation between psychedelic microdosing and improved mental well-being.
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PCC
Efficacy and Safety of Loxapine in Acute Agitation
Systematic Review

Efficacy and Safety of Loxapine in Acute Agitation

December 19, 2023

Loxapine was found to be more effective and faster regarding acute agitation control and was well-tolerated, with mildly or moderately severe adverse effects.
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Featured Systematic Review Research

PCC
When Medical Mistakes Leave Lasting Damage
Rounds in the General Hospital

When Medical Mistakes Leave Lasting Damage

September 8, 2026

Elements of disclosures and apologies (tone and nonverbal communication) play an important role after a medical error has occurred, and clinicians should allow ample time for discussion so that...
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PCC
When Obsession and Psychosis Become Indistinguishable
Case Report

When Obsession and Psychosis Become Indistinguishable

September 8, 2026

Differentiating obsessions from delusions is essential for accurate diagnosis and management, as comorbid obsessive-compulsive symptoms in schizophrenia complicate treatment and may influence cognitive and affective outcomes.
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JCP
The Regulatory Maze of Ketamine and Psychedelics with Benjamin Brody, MD
Podcast

The Regulatory Maze of Ketamine and Psychedelics with Benjamin Brody, MD

September 8, 2026

Benjamin Brody, MD, discusses ketamine's REMS-regulated future, esketamine safety, dysphoric dissociation, and what psilocybin approval means for psychiatry.
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JCP
Efficacy and Safety of Memantine for Children and Adults with ADHD
Systematic Review

Efficacy and Safety of Memantine for Children and Adults with ADHD

December 25, 2024

Although most studies involved small patient groups, memantine showed potential benefits in managing ADHD symptoms and had a favorable safety profile.
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PCC
Breast Cancer and Depression
Systematic Review

Breast Cancer and Depression

September 26, 2024

This scoping review explores depression prevalence, correlates, impact, and interventions in breast cancer patients, with a focus on the Indian context.
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JCP
Diagnostic Assessment via Telehealth vs Face-to-Face
Systematic Review

Diagnostic Assessment via Telehealth vs Face-to-Face

September 16, 2024

Several small studies suggest that telehealth holds promise for psychiatric assessments, especially when in-person evaluations are not feasible.
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PCC
Ketogenic Diet Therapies in Pediatric Epilepsy
Systematic Review

Ketogenic Diet Therapies in Pediatric Epilepsy

June 25, 2024

In this systematic review, the authors evaluated the effects of a ketogenic diet on epilepsy in children and adolescents.
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PCC
Obsessive-Compulsive Symptoms in Dementia
Systematic Review

Obsessive-Compulsive Symptoms in Dementia

June 18, 2024

The authors assess the literature on neurobiological mechanisms of obsessive-compulsive symptoms in dementia patients to shed light on the similarities and differences between these symptoms in dementia and in...
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PCC
Impact of Theta Burst Stimulation on MS
Systematic Review

Impact of Theta Burst Stimulation on MS

April 18, 2024

Theta burst stimulation interventions may hold promise in addressing specific multiple sclerosis symptoms, notably fatigue and spasticity.
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