Systematic Review

Recently published articles about Systematic Review

PCC
NMDA Receptor Antagonists in Pediatric Autism
Systematic Review

July 9, 2026

The authors review available data concerning the usage, efficacy, and side effects of memantine and amantadine, both NMDA receptor antagonists, in children with autism spectrum disorder.
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JCP
Thirty Years of the Diagnostic Criteria for Psychosomatic Research
Systematic Review

March 25, 2026

Findings indicate that the DCPR are an essential integration to psychiatric taxonomy, particularly in the setting of medical disease, with prognostic and therapeutic implications.
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JCP
Rechallenge of Lamotrigine After Rash: A Systematic Review
Systematic Review

December 31, 2025

Lamotrigine has been rechallenged safely in select cases, but it is critical to confirm that the initial rash did not have specific features of a severe rash in order...
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PCC
Psychiatric Adverse Effects of Hydroxychloroquine
Systematic Review

May 29, 2025

Hydroxychloroquine use is associated with various neuropsychiatric adverse effects, cognitive impairments, and behavioral changes.
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PCC
Exercise and Fibromyalgia Pain
Systematic Review

March 27, 2025

Adjunctive exercise therapies can be potentially beneficial in improving quality of life through reduction in pain catastrophizing.
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JCP
Inpatient Treatment of Suicidality
Systematic Review

January 8, 2025

Effective, rapid treatments that target suicidality in psychiatric inpatients are scarce in the existing literature and in clinical practice, underscoring the need for studies to identify and validate these...
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Recent JCP Articles on Systematic Review

JCP
Systematic Review of the Effects of Cannabis and Cannabinoids in PTSD Symptoms and Symptom Clusters
Systematic Review

February 14, 2024

This review of 14 studies did not find major benefits of cannabinoids in improving overall PTSD symptoms, although some benefits in cluster B and E symptoms were seen. Risks...
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JCP
Predictors and Risk Factors of Treatment-Resistant Depression
Systematic Review

November 13, 2023

Early identification of individuals with major depressive disorder who are likely to develop treatment-resistant depression (TRD) is needed. This study reviewed the literature to identify and categorize the predictors...
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JCP
Therapeutic Reference Range for Olanzapine
Systematic Review

July 19, 2023

A therapeutic reference range of 20–40 ng/mL for oral and long-acting injectable olanzapine yields optimal treatment effects in schizophrenia spectrum disorders. Dose reduction is not needed above 40 ng/mL...
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Recent PCC Articles on Systematic Review

PCC
Therapist-Guided Versus Self-Guided CBT
Systematic Review

March 21, 2024

Results were positive for the use of internet-based cognitive-behavioral therapy and encouraging for new methods of guided therapy and the inclusion of technology.
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PCC
Psychedelic Microdosing and Mental Health
Systematic Review

January 16, 2024

There is a growing body of evidence suggesting a positive correlation between psychedelic microdosing and improved mental well-being.
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PCC
Efficacy and Safety of Loxapine in Acute Agitation
Systematic Review

December 19, 2023

Loxapine was found to be more effective and faster regarding acute agitation control and was well-tolerated, with mildly or moderately severe adverse effects.
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Featured Systematic Review Research

PCC
Shame and Alcohol Use Disorder
Letter to the Editor

July 9, 2026

The authors focus on a barrier to successful treatment for AUD: a patient’s sense of shame regarding their own heavy drinking.
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JCP
Impact of VNS on Suicidal Ideation in Markedly Treatment-Resistant Major Depression: A RECOVER Study Report
Original Research ▶ Video

July 8, 2026

Findings suggest that active VNS reduces suicidal ideation (SI) and potentially induces SI remission among participants with chronic TRD and baseline SI.
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Beyond SSRIs: Why the Next Advance in GAD May Not Target Monoamines
news

July 7, 2026

DT120 (lysergide), a 5-HT2A agonist, eased GAD anxiety in trial. Beyond SSRIs/SNRIs, psychoplastogens offer new remission path.
JCP
Efficacy and Safety of Memantine for Children and Adults with ADHD
Systematic Review

December 25, 2024

Although most studies involved small patient groups, memantine showed potential benefits in managing ADHD symptoms and had a favorable safety profile.
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PCC
Breast Cancer and Depression
Systematic Review

September 26, 2024

This scoping review explores depression prevalence, correlates, impact, and interventions in breast cancer patients, with a focus on the Indian context.
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JCP
Diagnostic Assessment via Telehealth vs Face-to-Face
Systematic Review

September 16, 2024

Several small studies suggest that telehealth holds promise for psychiatric assessments, especially when in-person evaluations are not feasible.
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PCC
Ketogenic Diet Therapies in Pediatric Epilepsy
Systematic Review

June 25, 2024

In this systematic review, the authors evaluated the effects of a ketogenic diet on epilepsy in children and adolescents.
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PCC
Obsessive-Compulsive Symptoms in Dementia
Systematic Review

June 18, 2024

The authors assess the literature on neurobiological mechanisms of obsessive-compulsive symptoms in dementia patients to shed light on the similarities and differences between these symptoms in dementia and in...
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PCC
Impact of Theta Burst Stimulation on MS
Systematic Review

April 18, 2024

Theta burst stimulation interventions may hold promise in addressing specific multiple sclerosis symptoms, notably fatigue and spasticity.
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