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Buprenorphine for Pain in Sickle Cell Disease
Review Article

June 16, 2026

Buprenorphine is associated with improved functional outcomes as well as reduced ED visits, hospital admissions, and opioid use in patients with chronic pain related to sickle cell disease.
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JCP
The Art of Deprescribing: A Framework for Ending Medication with Joseph Goldberg, MD
Podcast

June 16, 2026

Dr. Joseph Goldberg discusses the ASCP deprescribing framework: when to stop medications, managing discontinuation, polypharmacy, and pregnancy considerations.
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JCP
Gestational Exposure to Sterol Biosynthesis Disrupting Drugs and Risk of Autism Spectrum Disorder
Clinical and Practical Psychopharmacology

June 15, 2026

Dr Andrade discusses a recent study of sterol biosynthesis disrupting drugs and argues that inadequate research methods disallow clinical application of the results.
JCP
Risk Factors for PTSD in a Diverse Cohort of Trauma-Exposed Youth: A 2-Year Longitudinal Study
Original Research

June 15, 2026

PTSD at the initial evaluation and at a 1-month follow-up strongly predicted later PTSD in trauma-exposed youth.
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PCC
The Patient in the Mirror
Original Research

June 11, 2026

The authors describe the unique challenges physicians may experience when they become patients and examine common physician-as-patient themes portrayed in media, including implications for clinical practice and medical education.
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PCC
Zolpidem for Severe Insomnia Associated With Delirium in Critical Illness
Case Report

June 11, 2026

A critically ill patient with sepsis and persistent delirium with treatment-refractory insomnia experienced rapid improvement in sleep continuity, delirium severity, and bedside cognitive performance with zolpidem.
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Original Research

JCP
Hallucinogen–Psychosis Associations Are Confounded by Baseline Psychiatric History
Original Research ▶ Video

June 10, 2026

Apparent associations between hallucinogen use and psychosis appear largely attributable to baseline psychiatric comorbidities rather than direct causal effects.
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PCC
Prevalence of Anxiety in an Underserved Population
Original Research

June 9, 2026

Generalized anxiety disorder is highly prevalent in underserved Venezuelan populations, particularly among women, highlighting the need for routine screening in primary care settings.
, , , et al
JCP
County-Level Variation in Substance Use Disorder Service Utilization by Insurance Payers and Self-Pay
Original Research ▶ Video

June 8, 2026

Across all examined payers, Medicaid funded a disproportionate share—over 50%—of SUD service expenditures.
, , , et al

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Placebo Effects in Alcohol, Cocaine, and Methamphetamine Use Disorder
Meta-Analysis

June 10, 2026

Placebo treatment led to reductions in craving scores across all three disorders, although statistical significance was achieved only in alcohol use disorder.
, , , et al
JCP
Inhaled Mebufotenin (GH001) for Adult Patients with Postpartum Depression
Original Research

June 3, 2026

Mebufotenin (GH001) demonstrated rapid and significant improvements in depressive symptoms and remission of postpartum depression.
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The Primary Care Companion for CNS Disorders

The Primary Care Companion for CNS Disorders seeks to advance the clinical expertise of primary care physicians and other health care professionals who treat patients with mental and neurologic illnesses.

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Catatonia Induced by D2R Antagonist Antiemetics
Case Report

June 4, 2026

The authors describe a rare case of catatonia correlated with abuse of D2R antagonist antiemetic medications in a 52-year-old man with multiple sclerosis.
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PCC
Improving Cardiac Arrest Survivorship
Rounds in the General Hospital

June 4, 2026

Affective states and conditions such as anxiety, PTSD, and depression are common in those who have survived a cardiac arrest, and untreated psychiatric symptoms are associated with worse cardiac…
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