Psychedelics

Psychedelics in psychiatry: emerging research on psilocybin, MDMA and ketamine. Clinical evidence, treatment protocols and therapeutic potential.

Recently published articles about Psychedelics

PCC
Psychological Adverse Effects of Psychedelic Use
Rounds in the General Hospital

June 25, 2026

This case-based review explores psychological adverse effects of psychedelic use, covering risk factors, trauma history, phenomenology, and evidence-based management strategies for clinicians.
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PCC
Medical Complications of Psychedelics
Rounds in the General Hospital

June 23, 2026

This case-based review covers acute complications, drug interactions, and long-term safety across psilocybin, MDMA, ketamine, and ibogaine, with practical guidance for clinicians.
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JCP
Hallucinogen–Psychosis Associations Are Confounded by Baseline Psychiatric History
Original Research ▶ Video

June 10, 2026

Apparent associations between hallucinogen use and psychosis appear largely attributable to baseline psychiatric comorbidities rather than direct causal effects.
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JCP
Efficacy and Safety of a Single Dose of Psilocybin for Chronic Suicidal Ideation
Original Research ▶ Video

May 13, 2026

A single psilocybin dose with psychological support was associated with rapid, large, and durable reductions in suicidal ideation and depressive symptoms.
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JCP
The Psychedelic Renaissance and Treatment-Resistant Depression with David Feifel, MD, PhD
Podcast

January 13, 2026

Dr. David Feifel discusses psilocybin's breakthrough potential for treatment-resistant depression, the psychedelic renaissance, and preparing for a new era in psychiatry.
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A Single LSD-Derived Dose Curbs Anxiety in Landmark Trial
news

September 8, 2025

A single dose of the LSD-derived drug MM120 dramatically reduced anxiety symptoms in adults with generalized anxiety disorder.

Featured Psychedelics Research

PCC
Pitfalls of Daily Fantasy Sports
Narrative Review

June 25, 2026

Daily fantasy sports are redefining gambling risk. This review examines addiction pathways, platform design, and mental health implications for vulnerable youth.
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PCC
Medical and Cultural Approach to OCD
Case Report

June 23, 2026

This case demonstrates successful management of severe religious OCD through medication optimization and psychotherapy over an 18-month treatment period.
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JCP
The Challenges of PTSD Prevention: Placing Benzodiazepine Use in Context
Commentary

June 22, 2026

The authors discuss the findings of a recent study by Rahamim et al.
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JCP
Psychedelic Therapies: One Drug, Multiple Treatments: Reply to Modesto-Lowe et al
Letter to the Editor

September 1, 2025

The authors reply to a letter by Modesto-Lowe et al regarding their survey of psychedelic practitioners’ views on psychological support.
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LSD Microdosing Doesn’t Appear to Help Treat Adult ADHD
news

March 19, 2025

A recent clinical trial found that microdosing LSD offers no significant benefit over a placebo in improving ADHD symptoms in adults.
JCP
Maintenance of Antidepressant Effect After 1 Dose of Psilocybin
Original Research

March 3, 2025

Over 52 weeks, a single administration of 25 mg psilocybin suggested longer maintenance of antidepressant effect than both 1 mg and 10 mg.
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JCP
Psychological Support in Psychedelic Therapy
Original Research

February 5, 2025

The survey reveals differences of opinion among psychedelic researchers, with a slight trend toward preference for an emotive approach to psychological support.
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PCC
Talking to Your Patients About Psychedelics
Rounds in the General Hospital

October 15, 2024

Given the precipitous increase in both scientific publications and public interest in psychedelics, clinicians should learn more about how they work, what they might work for, and what their...
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Researchers Uncover How Psilocybin Works in the Brain
news

July 18, 2024

Psilocybin disrupts brain networks related to reflective thinking, offering potential therapeutic benefits for mental health issues.

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