Gender Differences in Clinical Psychopharmacology

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Biological differences between men and women appear, at least in part, to be related to variation in levels and changes in sex steroids that subsequently interact with neurotransmitters. Reproductive-aged women have repetitive variations in sex hormones with each monthly cycle that influence the onset, chronicity, and outcome of a variety of psychiatric illnesses. Variations in brain structure and function and in pharmacokinetics may also contribute to psychiatric outcomes.​

J Clin Psychiatry 2005;66(9):1191