Original Research

JCP
Antipsychotic Efficacy of KarXT (Xanomeline−Trospium)
Original Research

image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ May 11, 2022

This post hoc analysis of phase 2 data evaluated rates and time course of response with the new combination oral agent KarXT (xanomeline−trospium) in the treatment of schizophrenia.
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PCC
Social and Emotional Health of College Students and COVID-19
Original Research

May 10, 2022

This study assessed the social and emotional health of university students in India as influenced by COVID-19 test results and the experience of isolation or quarantine.
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JCP
Daily Dose Effects of Risperidone on Metabolic Parameters
Original Research

May 9, 2022

This study investigated whether dose is a factor in the development of metabolic side effects with atypical antipsychotics.
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PCC
Resilience, Coping, Distress, and COVID-19
Original Research

May 5, 2022

The authors of this study assessed psychological resilience, coping, and related psychological distress in COVID-19 patients admitted to the hospital.
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PCC
Psychological Morbidity Among COVID-19 Survivors
Original Research

May 3, 2022

This study explored the psychological status of health care workers after recovery from COVID-19 and examined the sociodemographic and clinical factors associated with psychiatric morbidity.
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JCP
Epilepsy and Suicide Attempt
Original Research

May 2, 2022

From a sample of 1,229 adults who attempted suicide, this study found an elevated frequency of epilepsy and identified clinical factors that might play a role.
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JCP
Receipt of Antidepressants and Retention in Buprenorphine Treatment for OUD
Original Research

April 27, 2022

This study investigated whether receiving antidepressants increases the chance that patients with opioid use disorder will remain on buprenorphine treatment.
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JCP
Economic Burden of PTSD in the US
Original Research

April 25, 2022

Studies on the economic burden of posttraumatic stress disorder (PTSD) mostly focus on military populations and/or direct health care costs. This study estimated the economic burden of PTSD in...
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PCC
Psychocutaneous Medicine in Iraq
Original Research

April 21, 2022

In this study, the authors evaluated the knowledge and attitudes of Iraqi dermatologists regarding understanding, diagnosing, and treating psychocutaneous disorders.
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JCP
Transdiagnostic PRS Prediction of Mood Disorders
Original Research

April 20, 2022

Mood disorders often co-occur with behavior disorders in children and adolescents. This study explored if polygenic risk scores based on external genome-wide association studies of these disorders could improve...
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PCC
Care Management Intervention for Noncardiac Chest Pain
Original Research

April 19, 2022

This study describes the development, implementation, and preliminary feasibility of an 8-week multicomponent care management intervention for noncardiac chest pain.
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JCP
Co-Occurring Depression and Response During OUD Treatment
Original Research

April 18, 2022

This study looked at the relationship between opioid use disorder treatment and depression, and whether remission of depression is associated with lower relapse risk.
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JCP
ECT and Death by Suicide
Original Research

April 13, 2022

It is unclear if a course of electroconvulsive therapy (ECT) is associated with a decreased risk of death by suicide. This study examined the association of adequate exposure to...
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JCP
Effects of a Digital Medicine System on Psychiatric Hospitalization Rates for Adults With Schizophrenia
Original Research

April 11, 2022

This clinical trial investigated whether hospitalization rates improved when patients with schizophrenia were treated via a digital medicine system (aripiprazole tablets with sensor) versus oral standard-of-care therapy.
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JCP
Smartphone-Based Mental Health Screening in Adolescents and Young Adults
Original Research

April 6, 2022

This study used smartphone-based screening to explore depression, anxiety, well-being, and suicidality in young people in Mexico City.
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PCC
Health Anxiety and Lifestyle Behavior During COVID-19
Original Research

April 5, 2022

In this study, the authors assessed the intensity of negative emotions such as fear and anxiety and lifestyle behaviors among healthy individuals and those with chronic mental illness during...
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JCP
Economic Burden of MDD and Suicidality
Original Research

April 4, 2022

Acute suicidal ideation or behavior (SIB) that accompanies major depressive disorder (MDD) may produce a substantial economic burden. This study evaluated health care resource utilization and costs of commercially...
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PCC
Early Improvement in OCD
Original Research

March 31, 2022

This study examined if early response to SSRIs can reliably indicate future response to the same drug and compared 2 medications frequently used to treat OCD: sertraline and fluvoxamine.
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JCP
Differences Among Second-Generation Antipsychotics in Effects on HbA1c
Original Research

March 30, 2022

The antipsychotic blonanserin was associated with less change in glycated hemoglobin (HbA1c) levels than olanzapine, and changes in BMI were lower for both blonanserin and aripiprazole. Study results indicate...
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JCP
Association of Higher ALFF and Suicidal Ideation in BD
Original Research

March 30, 2022

Higher amplitude of low frequency fluctuation in the right hippocampus and thalamus has been found to be associated with suicidal ideation in major depressive disorder. The present study evaluated...
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JCP
Increased Admissions for Substance Use Disorder Among Older Adults, 2000–2017
Original Research

March 28, 2022

From 2000 to 2017, the number of older adults admitted for substance use disorder treatment increased by 203.7%, as compared to 13.0% in younger adults. This study looks at...
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PCC
Stigmatization Associated With COVID-19
Original Research

March 24, 2022

In this study, the authors survey and analyze the experience of stigma among patients with COVID-19 in Iran.
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JCP
Treatment Resistance in Late-Onset MDD
Original Research

March 23, 2022

This study investigated the association of physical versus psychiatric comorbidities with treatment resistance in older people with late-onset major depressive disorder.
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PCC
Use of the Telugu Insomnia Severity Index During COVID-19
Original Research

March 22, 2022

This study explored the factor structure of the Telugu-translated version of the Insomnia Severity Index, administered among primary care health workers in rural India during the COVID-19 pandemic.
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