Original Research
Original Research
Asenapine Transdermal System for Schizophrenia
December 15, 2020
Transdermal asenapine administration may address unmet needs in patients with schizophrenia, including improved adherence. This phase 3 study assessed efficacy and safety of HP-3070, an asenapine transdermal system (patch),...
Original Research
Predictors of ECT Treatment Response in Depression
December 15, 2020
Several clinical variables assumed to predict electroconvulsive therapy (ECT) outcome in major depressive disorder are interrelated. This study tries to disentangle this interdependence to distill the most important predictors...
Original Research
Socioeconomic Risk Factors for Medication Nonadherence
December 10, 2020
Nonadherence to psychiatric treatment is associated with poor outcomes. This study investigated the association of socioeconomic factors, race/ethnicity, and patient perceptions with medication adherence in individuals with depression.
Original Research
Antipsychotics for Homeless and Unstably Housed Veterans
December 8, 2020
Many homeless and unstably housed (HUH) adults have severe mental illness managed with antipsychotic medications. This study examined antipsychotic medication use and correlates of antipsychotic medication prescriptions among HUH...
Original Research
Adjunctive Pimavanserin and Sleep/Wakefulness in MDD
December 1, 2020
Adjunctive pimavanserin can reduce depressive symptoms and improve function in patients with major depression and inadequate antidepressant response. This analysis evaluated the effects of adjunctive pimavanserin on sleep/wakefulness disturbances.
Original Research
Depression Literacy Among Dermatologists
November 19, 2020
Increased depression literacy among dermatologists might play a vital role in early and successful detection and treatment of depression among their patients. This study investigated depression literacy among dermatologists...
Original Research
Association Between GlycA and Depressive Symptoms
November 17, 2020
Since the association of the inflammatory biomarker hs-CRP with depression is unclear, alternative inflammatory biomarkers of depression are needed. This study examined the association between the inflammatory biomarker GlycA...
Original Research
Routine Screening for Autoimmune Encephalitis
November 17, 2020
Autoimmune encephalitis (AE) is a highly treatable neurologic condition that can cause psychosis. This study estimated the cost-effectiveness of routine screening for AE compared with clinically targeted screening in...
Original Research
Happiness During Low-Dose Ketamine Infusion Predicts Treatment Response
November 10, 2020
Can we determine which patients will respond to ketamine just by observing their mood during the infusion? This study evaluated antidepressant outcomes with ketamine in 71 patients, focusing on ...
Original Research
COVID-19 Transmission in a Psychiatric Facility
November 5, 2020
This study reports the clinical characteristics and transmission rate of COVID-19 in an inpatient long-term care psychiatric facility to provide insight into transmission and symptom patterns, testing protocols, medical...
Original Research
Riluzole for Antidepressant-Resistant PTSD
October 27, 2020
Current pharmacologic treatments for posttraumatic stress disorder (PTSD) have shown limited efficacy. This study investigated the efficacy of the glutamatergic modulator riluzole for combat-related PTSD symptoms resistant to SSRIs...
Original Research
Child and Adolescent Tele-Partial Hospitalization Programs in Response to COVID-19Â
October 15, 2020
The COVID-19 pandemic has negatively impacted delivery of mental health services. This article describes the development and implementation of child and adolescent tele-partial hospitalization programs in response to the...
Original Research
Effect of SPN-812 (Viloxazine Extended-Release) on QTc Interval
October 13, 2020
This double-blind, randomized, crossover study investigated the effects of a supratherapeutic dose of SPN-812, a drug currently under investigation as a treatment for ADHD, on cardiac repolarization (QTc) in...
Original Research
Medications for DSM-5 PTSD
October 13, 2020
This retrospective study explored whether 5 medications for PTSD with efficacy in meta-analyses of randomized controlled trials—fluoxetine, paroxetine, sertraline, topiramate, and venlafaxine—are also effective in routine clinical practice.
Original Research
Delirium-Preventive Effects of Suvorexant in Real-World Settings
October 6, 2020
Although previous studies have demonstrated the efficacy of suvorexant for delirium prevention in limited randomized clinical trial settings, this study aimed to examine the effects of suvorexant on delirium...
