Original Research
Original Research
Long-Term Safety of Aripiprazole Lauroxil
August 18, 2020
Long-acting injectable (LAI) antipsychotics improve adherence, reduce treatment gaps, and improve clinical outcomes. This report describes the long-term safety, tolerability, and symptom trajectory with the LAI antipsychotic aripiprazole lauroxil.
Original Research
INP105 (Nasal Olanzapine) in Healthy Adults
June 30, 2020
Aside from intramuscular injection, few rapidly acting pharmacotherapeutic treatments are available for acute agitation. This study examined the safety and tolerability of INP105, a drug-device combination product that allows...
Original Research
Ganaxolone for Persistent Depression
June 9, 2020
Postmenopausal women may be deficient in the neuroactive steroid allopregnanolone. This study examined oral ganaxolone, an allopregnanolone analog, as augmentation therapy in postmenopausal women with inadequate response to traditional...
Original Research
Benzodiazepines, Antidepressants, and Antipsychotics and Mortality in Patients With Dementia
June 2, 2020
Patients with dementia often receive antipsychotics in combination with other psychotropic medications. This study compared mortality for antipsychotics combined with benzodiazepines or antidepressants with that for antipsychotic monotherapy.
Original Research
Relationships Between Executive Function and ADHD Symptom Improvement With Lisdexamfetamine
May 28, 2020
This study used post hoc path analyses to examine reciprocal relationships between improvement in executive function and ADHD symptoms from a double-blind, placebo-controlled study of lisdexamfetamine in adults with...
