Original Research
Original Research
COVID-19 Transmission in a Psychiatric Facility
November 5, 2020
This study reports the clinical characteristics and transmission rate of COVID-19 in an inpatient long-term care psychiatric facility to provide insight into transmission and symptom patterns, testing protocols, medical...
Original Research
Riluzole for Antidepressant-Resistant PTSD
October 27, 2020
Current pharmacologic treatments for posttraumatic stress disorder (PTSD) have shown limited efficacy. This study investigated the efficacy of the glutamatergic modulator riluzole for combat-related PTSD symptoms resistant to SSRIs...
Original Research
Child and Adolescent Tele-Partial Hospitalization Programs in Response to COVID-19Â
October 15, 2020
The COVID-19 pandemic has negatively impacted delivery of mental health services. This article describes the development and implementation of child and adolescent tele-partial hospitalization programs in response to the...
Original Research
Effect of SPN-812 (Viloxazine Extended-Release) on QTc Interval
October 13, 2020
This double-blind, randomized, crossover study investigated the effects of a supratherapeutic dose of SPN-812, a drug currently under investigation as a treatment for ADHD, on cardiac repolarization (QTc) in...
Original Research
Medications for DSM-5 PTSD
October 13, 2020
This retrospective study explored whether 5 medications for PTSD with efficacy in meta-analyses of randomized controlled trials—fluoxetine, paroxetine, sertraline, topiramate, and venlafaxine—are also effective in routine clinical practice.
Original Research
Delirium-Preventive Effects of Suvorexant in Real-World Settings
October 6, 2020
Although previous studies have demonstrated the efficacy of suvorexant for delirium prevention in limited randomized clinical trial settings, this study aimed to examine the effects of suvorexant on delirium...
Original Research
Benzodiazepines in Older Adults Receiving Antidepressants for Anxiety and Depression
September 29, 2020
This analysis of data from 2 clinical trials examined the effect of benzodiazepines on outcomes in older patients with generalized anxiety disorder or major depressive disorder, including the likelihood...
Original Research
Reminder-Focused Positive Psychiatry in ADHD and PTSD
September 3, 2020
Research has revealed the feasibility of positive psychiatry in youth. This study investigated the impact of reminder-focused positive psychiatry on PTSD and ADHD symptoms, neuroinflammation, vascular function, well-being, and...
Original Research
Long-Term Antidepressant Treatment and Risk of Dementia
August 25, 2020
The effects of antidepressants and treatment duration on the progression to dementia are currently unclear. This case-control study analyzed the effects of several antidepressants with different treatment durations on...
