Original Research
Original Research
INP105 (Nasal Olanzapine) in Healthy Adults
June 30, 2020
Aside from intramuscular injection, few rapidly acting pharmacotherapeutic treatments are available for acute agitation. This study examined the safety and tolerability of INP105, a drug-device combination product that allows...
Original Research
Ganaxolone for Persistent Depression
June 9, 2020
Postmenopausal women may be deficient in the neuroactive steroid allopregnanolone. This study examined oral ganaxolone, an allopregnanolone analog, as augmentation therapy in postmenopausal women with inadequate response to traditional...
Original Research
Benzodiazepines, Antidepressants, and Antipsychotics and Mortality in Patients With Dementia
June 2, 2020
Patients with dementia often receive antipsychotics in combination with other psychotropic medications. This study compared mortality for antipsychotics combined with benzodiazepines or antidepressants with that for antipsychotic monotherapy.
Original Research
Relationships Between Executive Function and ADHD Symptom Improvement With Lisdexamfetamine
May 28, 2020
This study used post hoc path analyses to examine reciprocal relationships between improvement in executive function and ADHD symptoms from a double-blind, placebo-controlled study of lisdexamfetamine in adults with...
Original Research
Guanfacine Extended-Release Improves ADHD Symptoms in Japanese Adults
April 14, 2020
Existing treatments for attention-deficit/hyperactivity disorder (ADHD) in adults, though effective, have limitations. This study examined the efficacy and safety of guanfacine extended-release in adults with ADHD.
Original Research
Heterogeneity in the Timing of Suicide Attempt Onset
April 7, 2020
Research suggests substantial age differences in suicide and suicide attempt rates. To better understand this heterogeneity, this study compared psychiatric, family history, and sociodemographic characteristics among 4 suicide attempter...
Original Research
Amphetamine Withdrawal After Lisdexamfetamine Cessation
March 26, 2020
Psychostimulant cessation can be associated with withdrawal symptoms. This study examined if dependence developed during lisdexamfetamine treatment for binge-eating disorder, as evidenced by presence of withdrawal symptoms after stopping...
