Original Research

JCP
Original Research

January 3, 2017

The risks of medication for bipolar disorder during pregnancy must be weighed carefully against the risks of untreated illness. Find out whether exposure to maternal illness and/or to medication...
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JCP
Original Research

December 28, 2016

Irritability and anger attacks affect about one-third of patients with major depressive disorder. This study by Fava et al evaluates adjunctive brexpiprazole as a strategy for patients with MDD...
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JCP
Original Research

December 28, 2016

Cortical thinning, identified during prodromal Alzheimer's disease, is a "candidate" biomarker used in clinical therapy trials. This study looked at change in cortical thickness after 1 year of donepezil...
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JCP
Original Research

December 28, 2016

Twenty US veterans kill themselves every day. What more can be done to stop this self-slaughter? Dialectical behavior therapy (DBT), which combines behavioral intervention with cognitive techniques of mindfulness,...
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JCP
Original Research

December 28, 2016

Understand the association between depression and levels of C-reactive protein (CRP) and fractional exhaled nitric oxide (FeNO).
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JCP
Original Research

December 28, 2016

Cognitive difficulties may be overlooked in treating patients with bipolar or unipolar depression, but 20% of patients report such symptoms. The authors of this article reanalyzed data from 2...
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JCP
Original Research

December 28, 2016

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JCP
Original Research

December 28, 2016

What's the next step when a patient doesn' t respond to an antipsychotic? Should you augment, switch medications, wait and see, or raise the dose? Read this study in...
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JCP
Original Research

December 28, 2016

Antipsychotics such as risperidone and aripiprazole are efficacious for controlling behavioral symptoms in children with intellectual disability or autism spectrum disorder, but they are also associated with adverse reactions...
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JCP
Original Research

December 28, 2016

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JCP
Original Research

December 28, 2016

When your 18- to 26-year-old patients respond poorly to the antipsychotic prescribed for their first episode of psychosis, what else can you try? In this RCT, taurine, which acts...
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JCP
Original Research

December 28, 2016

Are rates of depression and bipolar disorder going up? If so, why? To answer these questions, this Danish study looked at trends in diagnosed affective disorders over the last...
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JCP
Original Research

December 28, 2016

Read a study whether the Montgomery-Asberg Depression Rating Scale (MADRS) can assess the rapid onset of the antidepressant effect of a treatment in patients.
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JCP
Original Research

December 28, 2016

The worries that characterize generalized anxiety disorder are so pervasive and excessive that they distort cognition and create a considerable burden of illness. See what the authors of this...
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JCP
Original Research

December 6, 2016

Patients with insomnia and disrupted sleep are at increased risk of suicide. Check out this article to see if researchers found a link between antisuicidal response to ketamine and...
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JCP
Original Research

November 23, 2016

Several antipsychotics have shown efficacy for schizophrenia in controlled settings, but how effective are they in the long-term treatment of individuals in community settings? Learn how 7 antipsychotics compared...
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JCP
Original Research

November 23, 2016

As many as 25% of patients with first-episode psychosis experience nonremission or treatment resistance. Read this article to see whether initiating clozapine earlier in treatment can lead to better...
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JCP
Original Research

November 23, 2016

Is clozapine safe for patients with benign neutropenia? Many patients with lower than normal absolute neutrophil count do not qualify for clozapine therapy or are at risk of having...
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JCP
Original Research

November 23, 2016

Aripiprazole lauroxil, a long-acting injectable antipsychotic, demonstrated safety and efficacy in treating schizophrenia symptoms in a recent RCT. But how does it stack up against other antipsychotics in terms...
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JCP
Original Research

November 23, 2016

Knowing that patients with posttraumatic stress disorder and substance use disorder share impaired prefrontal cortex regulation, particularly at glutamate synapses in the nucleus accumbens, the authors conducted this first-ever...
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JCP
Original Research

November 23, 2016

Some have argued that changes to the diagnostic criteria for PTSD in the DSM-5 would increase rates of comorbidity between PTSD and other psychiatric disorders. Find out whether that...
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JCP
Original Research

October 26, 2016

How frequently do soldiers seek mental health treatment after being deployed? What types of care do they require? A study by Madsen et al looked at mental health service...
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JCP
Original Research

October 26, 2016

Read this article to learn whether age of onset of bipolar disorder or psychiatric illness is due to demographics or family psychiatric history.
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JCP
Original Research

October 26, 2016

If a patient with depression continues to have problems sleeping even after their depression is treated, what is the best course of action? In this RCT involving patients already...
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