Original Research

JCP
Original Research

December 28, 2016

When your 18- to 26-year-old patients respond poorly to the antipsychotic prescribed for their first episode of psychosis, what else can you try? In this RCT, taurine, which acts...
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JCP
Original Research

December 28, 2016

Are rates of depression and bipolar disorder going up? If so, why? To answer these questions, this Danish study looked at trends in diagnosed affective disorders over the last...
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JCP
Original Research

December 28, 2016

Read a study whether the Montgomery-Asberg Depression Rating Scale (MADRS) can assess the rapid onset of the antidepressant effect of a treatment in patients.
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JCP
Original Research

December 28, 2016

The worries that characterize generalized anxiety disorder are so pervasive and excessive that they distort cognition and create a considerable burden of illness. See what the authors of this...
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JCP
Original Research

December 6, 2016

Patients with insomnia and disrupted sleep are at increased risk of suicide. Check out this article to see if researchers found a link between antisuicidal response to ketamine and...
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JCP
Original Research

November 23, 2016

Several antipsychotics have shown efficacy for schizophrenia in controlled settings, but how effective are they in the long-term treatment of individuals in community settings? Learn how 7 antipsychotics compared...
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JCP
Original Research

November 23, 2016

As many as 25% of patients with first-episode psychosis experience nonremission or treatment resistance. Read this article to see whether initiating clozapine earlier in treatment can lead to better...
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JCP
Original Research

November 23, 2016

Is clozapine safe for patients with benign neutropenia? Many patients with lower than normal absolute neutrophil count do not qualify for clozapine therapy or are at risk of having...
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JCP
Original Research

November 23, 2016

Aripiprazole lauroxil, a long-acting injectable antipsychotic, demonstrated safety and efficacy in treating schizophrenia symptoms in a recent RCT. But how does it stack up against other antipsychotics in terms...
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JCP
Original Research

November 23, 2016

Knowing that patients with posttraumatic stress disorder and substance use disorder share impaired prefrontal cortex regulation, particularly at glutamate synapses in the nucleus accumbens, the authors conducted this first-ever...
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JCP
Original Research

November 23, 2016

Some have argued that changes to the diagnostic criteria for PTSD in the DSM-5 would increase rates of comorbidity between PTSD and other psychiatric disorders. Find out whether that...
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JCP
Original Research

October 26, 2016

How frequently do soldiers seek mental health treatment after being deployed? What types of care do they require? A study by Madsen et al looked at mental health service...
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JCP
Original Research

October 26, 2016

Read this article to learn whether age of onset of bipolar disorder or psychiatric illness is due to demographics or family psychiatric history.
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JCP
Original Research

October 26, 2016

If a patient with depression continues to have problems sleeping even after their depression is treated, what is the best course of action? In this RCT involving patients already...
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JCP
Original Research

October 26, 2016

Characterizing the role of inflammation in depression is an important part of identifying potential targets for intervention. Zheng and colleagues assessed plasma dipeptidyl peptidase-4 activity, inflammatory markers, and neuropeptide...
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JCP
Original Research

October 26, 2016

Use of psychiatric emergency departments in the United States has risen substantially in recent decades. Read this article to see how well a clinical tool performed in triaging emergency...
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JCP
Original Research

October 26, 2016

When psychiatrists officially warn patients with serious mental illness that they should not drive, do the patients listen? This study looked into rates of repeat accidents and psychiatric hospitalization...
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JCP
Original Research

October 26, 2016

Late-onset frontal lobe syndrome may lead you on the wrong path when diagnosing your patients. Read this article to see how specific subtyping of clinical symptoms can help you...
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JCP
Original Research

October 26, 2016

Lurasidone's favorable safety profile in younger adults suggests it would be a good candidate for the treatment of episodes of bipolar depression in older adults. For your patients 55...
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JCP
Original Research

October 26, 2016

As many as a third of adult OCD patients have a tic disorder. This study compared clinical profiles between tic-related and tic-free OCD patients, and explored the influence of...
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JCP
Original Research

October 26, 2016

Neurofeedback has been proposed as a promising intervention for ADHD. In this RCT, Geladé and colleagues compare it with methylphenidate and with physical activity for effects on ADHD symptoms...
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JCP
Original Research

October 26, 2016

Read a study comparing oral antipsychotics with paliperidone palmitate in a veteran population to evaluate health care resource utilization with each type of schizophrenia treatment.
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JCP
Original Research

October 26, 2016

What makes some patients more adherent to psychiatric treatment than others? Discover how their beliefs about who or what controls their medications influences their likelihood for adhering to treatment...
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JCP
Original Research

October 26, 2016

Despite substantial criticism, polygraphy remains the only biological method of lie detection in use today. How does its accuracy compare of that of functional MRI? Read this article by...
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