Psychiatrist in professional attire presenting clinical expertise

Roger S. McIntyre, MD, FRCPC

Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada; Department of Pharmacology and Toxicology, University of Toronto, Ontario, Canada

  • 87Articles
  • 534.1KReads
  • 2001–2026Active
  • 223Collaborators
  • 2.3KCitations

About

Roger S. McIntyre is affiliated with the Department of Psychiatry and the Department of Pharmacology and Toxicology at the University of Toronto. With a publication record spanning from 2001 to 2026, McIntyre has contributed extensively to clinical topics including major depressive disorder, bipolar disorder, schizophrenia and schizoaffective disorders, child and adolescent psychiatry, patient care, weight management, cognition, and neurology. His work explores pharmacodynamic effects following antidepressant cessation, the role of GLP-1 receptor agonists in psychiatric treatment, metabolic dysfunction screening in severe mental disorders, and innovations in precision psychiatry. McIntyre frequently collaborates with authors such as Michael E. Thase and Christoph U. Correll.

Publications

JCP
Co-occurrence of Depression and Obesity: Implications for Practice and the Discovery of Targeted and Mechanistically Informed Therapeutics
Commentary

Co-occurrence of Depression and Obesity: Implications for Practice and the Discovery of Targeted and Mechanistically Informed Therapeutics

June 3, 2024

Dr McIntyre discusses the implications of recent research by Baek et al.
JCP
Risk-Sensitive Decision-Making and Self-Harm
Original Research

Risk-Sensitive Decision-Making and Self-Harm

September 6, 2023

Greater risk-taking has been associated with suicide attempts in youth with major depression. This study examined whether the association between self-harm and risk-sensitive decision-making is true for bipolar disorder...
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JCP
Vortioxetine vs Desvenlafaxine in Patients With MDD
Original Research

Vortioxetine vs Desvenlafaxine in Patients With MDD

May 22, 2023

Compared with desvenlafaxine, vortioxetine was associated with higher rates of symptomatic and functional remission, better daily and social functioning, and greater treatment satisfaction in patients with major depression and...
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PCC
Screening for Bipolar Disorder and Evaluating the RMS
Original Research

Screening for Bipolar Disorder and Evaluating the RMS

April 25, 2023

Health care providers found the Rapid Mood Screener, a new bipolar I disorder screening tool, to be superior to the widely used Mood Disorder Questionnaire in sensitivity/specificity, brevity, practicality,...
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JCP
Efficacy of Lumateperone in Bipolar Depression With Mixed Features
Original Research

Efficacy of Lumateperone in Bipolar Depression With Mixed Features

April 24, 2023

Lumateperone significantly improved depression symptoms, disease severity, and quality of life in patients with bipolar depression with mixed features.
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JCP
Patient Functioning and Life Engagement: Treatment Goals in MDD
Insights

Patient Functioning and Life Engagement: Treatment Goals in MDD

September 7, 2022

Patients with MDD often report lack of motivation and energy and a feeling of disengagement from their own lives. Here, experts discuss treatment strategies that may be favorable for...
, , , et al
JCP
Patient Functioning, Life Engagement, and Treatment Goals in Major Depressive Disorder
Academic Highlights

Patient Functioning, Life Engagement, and Treatment Goals in Major Depressive Disorder

September 7, 2022

Patients with MDD often report lack of motivation and energy and a feeling of disengagement from their own lives. Here, experts discuss treatment strategies that may be favorable for...
, , , et al
JCP
Patient Functioning and Life Engagement: Treatment Goals in Schizophrenia
Insights

Patient Functioning and Life Engagement: Treatment Goals in Schizophrenia

August 17, 2022

Many people with schizophrenia feel isolated and disengaged from their own lives even when symptoms are under control. Here, experts discuss assessment of life engagement and treatment strategies that...
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JCP
Patient Functioning, Life Engagement, and Treatment Goals in Schizophrenia
Academic Highlights

Patient Functioning, Life Engagement, and Treatment Goals in Schizophrenia

August 17, 2022

Many people with schizophrenia feel isolated and disengaged from their own lives even when symptoms are under control. Here, experts discuss assessment of life engagement and treatment strategies that...
, , , et al
JCP
Patient Functioning and Life Engagement: Unmet Needs in MDD and Schizophrenia
Insights

Patient Functioning and Life Engagement: Unmet Needs in MDD and Schizophrenia

August 8, 2022

Besides achieving symptom relief and improved functioning, many patients with serious mental illness wish to connect more with others and feel engaged with their lives. Five experts discuss life...
, , , et al
JCP
Patient Functioning and Life Engagement: Unmet Needs in MDD and Schizophrenia
Academic Highlights

Patient Functioning and Life Engagement: Unmet Needs in MDD and Schizophrenia

August 3, 2022

Besides achieving symptom relief and improved functioning, many patients with serious mental illness wish to connect more with others and feel engaged with their lives. Five experts discuss life...
, , , et al
JCP
Distinguishing Bipolar Disorder From MDD: Points to Remember
Insights

Distinguishing Bipolar Disorder From MDD: Points to Remember

April 13, 2021

Dr Roger S. McIntyre highlights 3 important considerations in the differential diagnosis of bipolar disorder and major depressive disorder: age at onset, episode recurrence, and delayed emergence of mania

Physicians Postgraduate Press, Inc. (PPP) makes no warranties about the accuracy or completeness of any information published in The Journal of Clinical Psychiatry or other PPP materials, and disclaims liability for any use or non-use of that information. Clinicians should not rely solely on these materials and should exercise their own professional judgment when making patient care decisions on an individualized basis.

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