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The Journal of
Clinical Psychiatry
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The Journal of Clinical Psychiatry

Insights September 7, 2022

Patient Functioning and Life Engagement: Treatment Goals in MDD

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Many people with major depressive disorder feel isolated and disengaged from their own lives even when symptoms are under control. Here, experts discuss assessment of life engagement and treatment strategies that optimize the chances of achieving it.

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New Series The JCP Podcast Lamotrigine clearance can rise by 200% to 300% in pregnancy, turning a previously stable dose into therapeutic failure, while the postpartum reset can make that same dose toxic fast. This conversation gets practical about monitoring, tapering, and why screening for bipolar disorder in postpartum depression can change treatment decisions.

About the Authors

The Journal of Clinical Psychiatry June 2026 cover with featured article titles

Vol 87 • 2026 • Number 2

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