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Case Report
Oral Glutamatergic Modulation with Dextromethorphan and Piracetam for Refractory Bipolar Disorder With OCD
February 23, 2026
Three patients with combined bipolar disorder and OCD experienced remission of depressive, anxious, and obsessive-compulsive symptoms after piracetam was added to dextromethorphan.
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Featured Case Report Research
Original Research
Comparing Risk Prediction for Suicide Attempts and Deaths After Emergency Department Visits
March 4, 2026
Distinct factors predict nonfatal and fatal suicidal events. Male sex and depression are the strongest predictors for fatal events; being under 65 years of age and suicidal ideation are...
Original Research
Outcomes and Practice Patterns of LAI Versus Oral Antipsychotics Among Patients With Bipolar I Disorder in the US
March 2, 2026
Long-acting injectable antipsychotics, especially second-generation formulations, are associated with reduced rehospitalization in bipolar I disorder compared to oral antipsychotics.
Case Report
When the Labs Don’t Add Up: Factitious Disorder and Successful Treatment
January 27, 2026
This case of a 37-year-old woman, who presented to the ED with recurrent syncope and acute kidney injury, demonstrates successful long-term treatment of factitious disorder, highlighting the complexities of...