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Recently published articles about Difficult to Treat Depression
Article
An 8-Week Randomized, Double-Blind Trial Comparing Efficacy, Safety, and Tolerability of 3 Vilazodone Dose-Initiation Strategies Following Switch From SSRIs and SNRIs in Major Depressive Disorder
August 6, 2015
Do patients clinically benefit from a switch from initial antidepressant treatment to vilazodone? How often do they experience adverse events? To answer these questions, the authors of this study...
Article
Repetitive Transcranial Magnetic Stimulation for Treatment-Resistant Depression in Adult and Youth Populations: A Systematic Literature Review and Meta-Analysis
May 15, 2015
Repetitive transcranial magnetic stimulation (rTMS) is a promising nonivasive, nonpharmaceutical treatment for treatment-resistant depression. Set out with this study as it explores the safety, efficacy, and optimal protocal of...
Article
Reducing the Burden of Difficult-to-Treat Major Depressive Disorder: Revisiting Monoamine Oxidase Inhibitor Therapy
October 31, 2013
Difficult-to-treat depression, such as depression with atypical or anxious symptoms, treatment-resistant depression, or depression with frequent recurrence, is a challenging real-world health issue. This critical review of the literature...
Article
Beneficial Effects of Adjunctive Aripiprazole in Major Depressive Disorder Are Not Dependent on Antidepressant Therapy History: A Post Hoc Analysis of 3 Randomized, Double-Blind, Placebo-Controlled Trials
November 22, 2012
Patients with depression often do not respond to the initial treatment and clinicians must then adjust therapy. The objective of this study was to determine whether switching within or...
Article
Efficacy of Adjunctive Aripiprazole in Major Depressive Disorder: A Pooled Response Quartile Analysis and the Predictive Value of Week 2 Early Response
May 31, 2012
This post hoc analysis of 3 similarly designed randomized, double-blind, placebo-controlled phase 3 studies investigated the efficacy and safety of adjunctive aripiprazole to standard antidepressant therapy (ADT) in patients...
