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Recently published articles about Difficult to Treat Depression

JCP
Original Research

March 16, 2021

How prevalent is treatment-resistant depression (TRD), and what proportion of the burden of medication-treated major depressive disorder is accounted for by TRD? This study explores those questions using the...
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PCC
Review Article

December 31, 2020

Exercise, yoga, and tai chi are commonly used complementary approaches for health and wellness. This review aims to synthesize the evidence for exercise, yoga, and tai chi in the...
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JCP
Commentary

November 10, 2020

This commentary discusses the implications of a recent article by Chen et al that investigated whether a patient's happiness level during ketamine infusion can predict their eventual antidepressant response...
JCP
Original Research

November 10, 2020

Can we determine which patients will respond to ketamine just by observing their mood during the infusion? This study evaluated antidepressant outcomes with ketamine in 71 patients, focusing on ...
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PCC
Case Report

July 9, 2020

Management of resistant depression is challenging, as many patients have tried multiple medications and psychotherapy with no success. This report describes a case of resistant depression successfully treated with...
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PCC
Original Research

June 25, 2020

Food supplements or probiotics have been studied as adjunctive therapy to antidepressants and psychotherapy for depression. This study assessed the effects of the combination of SAMe and Lactobacillus plantarum...
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PCC
Letter to the Editor

June 4, 2020

In this letter to the editor, the authors describe a small population of patients unable to receive ECT due to medical risks who received ketamine for depression.
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PCC
Original Research

April 30, 2020

Stress is associated with the onset, maintenance, and recurrence of depression. This study aimed to investigate the feasibility of stress management and resiliency training for enhancing resiliency in a...
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JCP
Original Research

April 28, 2020

Read a study about esketamine nasal spray (oral antidepressant) and it's long-term safety, tolerability, and efficacy for treatment-resistant depression (TRD).
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JCP
Letter to the Editor

November 12, 2019

Few studies have evaluated optimal dosing of intravenous (IV) ketamine for treatment-resistant depression (TRD). This report analyzes data from previous studies of IV ketamine to assess the association between...
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JCP
Original Research

October 15, 2019

This study aimed to estimate the prevalence of metabolic syndrome and its components in patients with treatment-resistant depression and determine correlations with sociodemographic, clinical, and treatment-related factors—read the article...
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JCP
Review Article

June 4, 2019

To optimize treatment choices for patients with treatment-resistant depression (TRD), TRD should be defined accurately and unambiguously. This review examines extant descriptions and staging models of TRD and posits...
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Consensus Report on XT Use in Practice

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Figure: Graphic promoting Consensus Report on Xanomeline-Trospium; colorful net design shown with JCP logo in lower left.

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