The Journal of Clinical Psychiatry The Journal of Clinical Psychiatry

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Clinical Psychiatry

Empowering mental health professionals with peer-reviewed psychiatric research and insights

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JCP
Accumulation of Reproductive Safety Data for SGAs
Commentary

June 8, 2022

This commentary on an article by Yakuwa and colleagues calls for an acceleration of the acquisition of clinical data on the safety of second-generation antipsychotics for pregnant women and…
JCP
Pregnancy Outcomes With First-Trimester SGA Exposure
Original Research

June 8, 2022

In Japan, information regarding the effects of antipsychotics on the fetus during pregnancy is limited. This Japanese study examined the association between the use of antipsychotics during pregnancy and…
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JCP
Psychiatric Patients Who Do Not Believe They Deserve to Get Better
Brief Report

June 8, 2022

This study of 405 patients in a partial hospital program examined the prevalence of the belief of “undeservingness” (ie, that one does not deserve to be treated) and the…
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JCP
Transdermal HP-3070 for Hostility in Schizophrenia
Original Research

June 6, 2022

Schizophrenia is sometimes accompanied by aggressive, hostile behavior, particularly during the acute phase. This post hoc analysis of a phase 3 study examines the efficacy of transdermal asenapine (HP-3070)…
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JCP
Suicide Risk in a National VA Sample
Original Research

June 6, 2022

Predicting suicide is difficult, as suicidal behavior is not linked solely to any single behavior or psychiatric diagnosis. This study compared risk of suicidal behavior among a transdiagnostic sample…
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JCP
Long-term Outcomes of Early Use of LAIs in Schizophrenia
Original Research

June 1, 2022

Using data from the Taiwan National Health Insurance Research Database, the authors compared long-term effectiveness of switching to long-acting injectable antipsychotics versus remaining on oral antipsychotics.
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JCP
Efficacy and Safety of AXS-05 (Dextromethorphan-Bupropion) in MDD
Original Research

May 30, 2022

Altered glutamatergic neurotransmission has been implicated in the pathogenesis of depression. This phase 3 trial evaluated the efficacy and safety of AXS-05 (dextromethorphan-bupropion) in the treatment of major depressive…
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JCP
ADHD, ASD, and Other Neurodevelopmental Outcomes Associated With Antipsychotic Exposure During Pregnancy
Clinical and Practical Psychopharmacology

May 30, 2022

Dr Andrade discusses the implications of 2 recent large cohort studies examining risk of neurodevelopmental disorders after gestational exposure to antidepressants.
JCP
Antidepressant Drugs and Health-Related QoL: A Guide to Examining a “Viral” Research Paper
Clinical and Practical Psychopharmacology

May 25, 2022

A recent study reporting no improvement in health-related quality of life with antidepressants went “viral” in the mass media. Here, Dr Andrade considers the shortcomings of the study and…
JCP
Should Blind Psychiatrists Be Paid Less?
Commentary

May 23, 2022

Dr Zimmerman comments on a recent meta-analysis by Scott and colleagues on the use of video-based telehealth in treatment of PTSD.
JCP
Telehealth vs Face-to-Face Management for PTSD in Primary Care
Meta-Analysis

May 23, 2022

This timely meta-analysis compared telehealth with face-to-face care for patients with PTSD, examining PTSD severity, QoL, therapeutic alliance, and other aspects.
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JCP
Clozapine Use in Singapore and Hong Kong
Original Research

May 18, 2022

This survey investigated clinicians’ use of clozapine for schizophrenia, beliefs about its effectiveness, and concerns regarding this medication.
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