This work may not be copied, distributed, displayed, published, reproduced, transmitted, modified, posted, sold, licensed, or used for commercial purposes. By downloading this file, you are agreeing to the publisher’s Terms & Conditions.


Peptides and Psychiatry, Part 3: Substance P and Serendipity: Novel Psychotropics Are a Possibility

Stephen M. Stahl

Published: March 31, 1999

Article Abstract

Progress in psychopharmacology is largely the story of serendipitous clinical observations followed by controlled clinical trials. The most recent chapter in this story is the unexpected finding of antidepressant properties for a substance P antagonist. Scientific rationale predicts that such agents should be blockers of neurogenic inflammation or pain, but clinical testing for these actions has been disappointing.

Some JCP and PCC articles are available in PDF format only. Please click the PDF link at the top of this page to access the full text.

Related Articles

Volume: 60

Quick Links: