The Journal of
Clinical Psychiatry

Volume 87 • 2026 • 2

Meta-Analysis

Placebo Effects in Alcohol, Cocaine, and Methamphetamine Use Disorder: A Systematic Review and Meta-Analysis

J Clin Psychiatry 2026;87(2):25r16118

Pim B. van der Meer, MD, PhD; Jan W. Schoones, MSc; Jurjen Luykx, MD, PhD; Olaf M. Dekkers, MD, PhD; Marta Fiocco, PhD; Cornelis Kees Kramers, MD, PhD; Arnt Schellekens, MD, PhD; Albert Batalla, MD, PhD

Narrative Review

Measuring What Matters: Further Validation for the Tardive Dyskinesia Impact Scale, a Novel Patient-Reported Outcome Measure in Valbenazine Clinical Trials

J Clin Psychiatry 2026;87(2):25nr16047

Morgan Bron, PharmD, MS; Susan D. Mathias, MPH; Donald E. Stull, PhD; Hui Zhang, PhD; Michelle Turner, MS; Eduardo Dunayevich, MD; Ashok Parameswaran, MD; Dawn Vanderhoef, PhD, DNP, PMHNP-BC, FAANP; M. Mercedes Perez-Rodriguez, MD, PhD; Christoph U. Correll, MD

Systematic Review

Thirty Years of the Diagnostic Criteria for Psychosomatic Research (DCPR): A Systematic Review and Discussion of Clinical Implications

J Clin Psychiatry 2026;87(2):25r16276

Jenny Guidi, PsyD, PhD; Nicoletta Sonino, MD; Giovanni A. Fava, MD

Original Research

Using Natural Language Processing to Evaluate Differences in Psychotherapeutic Services for Posttraumatic Stress Disorder in a Suicide-Risk-Stratified Veteran Sample

J Clin Psychiatry 2026;87(2):25m15904

Maxwell Levis, PhD; Monica Dimambro, MS; Joshua Levy, PhD; Natalie Riblet, MD, MPH; Brian Shiner, MD, MPH

Original Research

Nonsuicidal Self-Injury and Its Association With Suicidal Ideation and Negative Affect: A 12-Month Ecological Momentary Assessment

J Clin Psychiatry 2026;87(2):25m16072

Adrián Alacreu-Crespo, PhD; Ana Maria De Granda-Beltrán, MD; Elena Abances-Utrilla, MSc; Sandra Grijalba, BsC; Laura Jiménez-Muñoz, PhD; Maria Luisa Barrigón, MD, PhD; Philippe Courtet, MD, PhD; Jorge López-Castromán, MD, PhD; Alejandro Porras-Segovia, MD, PhD; Enrique Baca-García, MD, PhD

Original Research

Suicide Risk and Veterans Health Administration Utilization Among Those With a Documented Suicide Attempt in the US Military

J Clin Psychiatry 2026;87(2):25m16168

Mark A. Reger, PhD; Sybil W. Morley, MPH; Kevin D. Masters, MLS; Brady M. Stephens, MS

Original Research

A Phase 2b Multicenter Study to Evaluate Basmisanil as an Adjunctive Treatment in Patients With Cognitive Impairment Associated With Schizophrenia

J Clin Psychiatry 2026;87(2):25m16022

Daniel Umbricht, MD; Markus Abt, PhD; Michael Derks, PhD; Maria-Clemencia Hernandez, PhD; Nikhat Parkar, MA; Diana Negron, MSc; Annette Koerner, PhD; Stefan Holiga, PhD; Celia Goeldner, PhD

Original Research

Cognitive Behavioral Therapy Following Esketamine for Major Depression and Suicidal Ideation for Relapse Prevention: The CBT-ENDURE Randomized Trial

J Clin Psychiatry 2026;87(2):25m16285

Samuel T. Wilkinson, MD; Brandon M. Kitay, MD, PhD; Matthew Macaluso, DO; Mia C. Santucci, BA; Kristina Kumpf, MA; Cindy Voghell, BS; Lauren Astorino, MSN; Rachel Hershenberg, PhD; Valeria Martinez-Kaigi, PhD; Tiffany Nowell, PhD; Michael E. Thase, MD; Gerard Sanacora, MD, PhD; T. Greg Rhee, PhD

Original Research

Effects of Experimental Intermittent Theta Burst Stimulation on Negative Symptoms of Schizophrenia: A Double-Blind Sham-Controlled Study

J Clin Psychiatry 2026;87(2):25m16093

Nand Kumar, MD; Shiv Prasad, MD; M. V. Padma Srivastava, MD; M. Kalaivani, MD; Maria Madiha, PhD; Vaibhav Patil, MD; Manoj Kumar, MD

Original Research

Aripiprazole Once-Monthly for Patients Diagnosed With Schizophrenia: Number Needed to Treat, Number Needed to Harm, and Likelihood to be Helped or Harmed

J Clin Psychiatry 2026;87(2):26m16359

Leslie Citrome, MD, MPH; Karimah S. Bell Lynum, PharmD; Zhen Zhang, PhD; Norman Atkins, Jr, PhD; Anne M. Hutson Walker, PhD; Murat Yildirim, MD, PhD

Original Research ▶ Video

Efficacy and Safety of a Single Dose of Psilocybin for Chronic Suicidal Ideation: An Open-Label Trial

J Clin Psychiatry 2026;87(2):26m16338

Andrew van der Vaart, MD, PhD; Jeffrey LaPratt, PsyD; Kimberly Swartz, BSN; Audrey Shoultz, BS; Margo Lauterbach, MD; Trisha Suppes, MD, PhD; Harold A. Sackeim, PhD; Scott T. Aaronson, MD

Original Research

Differential Impact of Cholecystokinin and Ghrelin on 2-Year Avoidant/Restrictive Food Intake Disorder Symptoms

J Clin Psychiatry 2026;87(2):25m16046

Vittoria Trolio, BA; Sophie Scharner, MD; Nassim Tabri, PhD; Hang Lee, PhD; Helen Burton-Murray, PhD; Kendra R. Becker, PhD; P. Evelyna Kambanis, PhD; Lauren Breithaupt, PhD; Julia Gydus, BSc; Laura Holsen, PhD; Madhusmita Misra, MD; Kamryn T. Eddy, PhD; Nadia Micali, MD, PhD; Elizabeth A. Lawson, MD; Jennifer J. Thomas, PhD

Original Research

Viloxazine Extended Release in Adults With Attention-Deficit/Hyperactivity Disorder and Depression and/or Anxiety Symptoms: Results From a Decentralized, Open-Label, Phase 4 Trial

J Clin Psychiatry 2026;87(2):25m16234

Lenard A. Adler, MD; V. Rose Lieberman, MS; Leslie Brijbasi, MBA; Greg W. Mattingly, MD; Ilmiya Yarullina, MD; Yuan Li, PhD; Jami Earnest, PharmD, BCPP; Jonathan Rubin, MD, MBA

Original Research

Outcomes and Practice Patterns of Long-Acting Injectable Versus Oral Antipsychotics Among Patients With Bipolar I Disorder in the United States: A Hospital Database Analysis

J Clin Psychiatry 2026;87(2):25m16154

Sigal Kaplan, PhD, BPharm; Zenobia Dotiwala, MS; Julian Casciano, MS; Mark Suett, MB, ChB; Arti Phatak, PharmD, BCPS; Ying Zhang, PhD; Lynda Krasenbaum, MSN, ANP-BC; Martha Sajatovic, MD

Original Research

Comparing Risk Prediction for Suicide Attempts and Deaths After Emergency Department Visits for Individuals With Mental Health Disorders

J Clin Psychiatry 2026;87(2):25m16070

Steven C. Marcus, PhD; Sara Wiesel Cullen, PhD, MSW; Ming Xie, MS; Tony Liu, PhD; Nathaniel J. Williams, PhD, MSW; Timothy Schmutte, PsyD; Lyle H. Ungar, PhD; Nicholas C. Cardamone, MSEd; Mark Olfson, MD, MPH

Original Research

Safety and Efficacy of Maintenance Treatment With Aripiprazole Once-Monthly in Black/African American Adults Diagnosed With Bipolar I Disorder: Post Hoc Analysis of a 52-Week, Open-Label Study

J Clin Psychiatry 2026;87(2):25m16114

Karimah S. Bell Lynum, PharmD, MBA, BCPP; Pedro Such, MD; Zhen Zhang, PhD; Amica Simmons-Yon, PharmD, PhD; Norman Atkins, Jr, PhD, MBA; William Lawson, MD, PhD, DLFAPA; Joseph F. Goldberg, MD

Original Research

The Efficacy of Olanzapine/Samidorphan on Negative Symptoms: A Post Hoc Analysis of 56-Week Treatment in Patients With Schizophrenia

J Clin Psychiatry 2026;87(2):25m16170

Roger S. McIntyre, MD; Desiree M. Matthews, PMHNP-BC; Christina Arevalo, MS; David McDonnell, MD; Christoph U. Correll, MD

Original Research

Temporal Dynamics of Antidepressant Response Following Brexanolone Treatment in Postpartum Depression

J Clin Psychiatry 2026;87(2):25m16144

Rachel Kozik, BA; Riah Patterson, MD; Elizabeth Andersen, PhD; Frank W. Putnam, MD; David Rubinow, MD

Original Research

Neuropsychiatric Symptom Clusters and Their Association With Brain Structure in Alzheimer Disease

J Clin Psychiatry 2026;87(2):25m16192

Original Research

Postmarketing Safety of Transcranial Magnetic Stimulation: A 10-Year MAUDE Database Analysis of Adverse Events and Technological Advancements

J Clin Psychiatry 2026;87(2):25m16155

Ali Imam Awan, MBBS; Nida Waheed, MBBS; Rida Zahra, MBBS; Allah Dad, MBBS; Deepan Singh, MD

Original Research

Correlates and Predictors of Criminal Legal Involvement in People With First-Episode Psychosis

J Clin Psychiatry 2026;87(2):25m15991

Faith Scanlon, PhD; Kim T. Mueser, PhD; Corinne Cather, PhD

Commentary

The Patient Perspective on Tardive Dyskinesia

J Clin Psychiatry 2026;87(2):26com16440

Nina R. Schooler, PhD

Commentary

Mind-Body Integration and East-West Fusion for Modern Medicine: Insights From the Diagnostic Criteria for Psychosomatic Research

J Clin Psychiatry. 2026;87(2):26com16376

Jianxin Cao, MD; Qiaoli Zhang, MD

Commentary

Biography Inscribed in Biology: The Diagnostic Criteria for Psychosomatic Research and the Embodiment of Lived Experience

J Clin Psychiatry 2026;87(2):26com16386

Ralph I. Horwitz, MD

Commentary

The Demoralization Construct in Clinical Practice and Research

J Clin Psychiatry 2026;87(2):26com16383

John M. de Figueiredo, MD, ScD

Clinical and Practical Psychopharmacology

Proton Pump Inhibitors and the Risk of Dementia

J Clin Psychiatry 2026;87(2):26f16420

Chittaranjan Andrade, MD

Clinical and Practical Psychopharmacology

Insomnia, Sleep, and the Use of Sedative-Hypnotic Drugs: Practical Notes

J Clin Psychiatry 2026;87(2):26f16467

Chittaranjan Andrade, MD

Clinical and Practical Psychopharmacology

Association of Selective Serotonin Reuptake Inhibitor and Other Antidepressant Drugs With Dental Implant Failure

J Clin Psychiatry. 2026;87(2):26f16375

Chittaranjan Andrade, MD

ASCP Corner

Life After Clozapine: Managing Treatment-Resistant Schizophrenia When Clozapine Is No Longer an Option

J Clin Psychiatry 2026;87(2):26ac16364

Julieta Ramirez, MD; Christoph U. Correll, MD

Brief Report

Inconsistent MAOI Dietary Guidance From Major AI Chatbots: A Brief Clinical Evaluation

J Clin Psychiatry 2026;87(2):26br16313

Cláudia Hara, MD, MSc, PhD; Caio Couto Pereira, MD; Fábio Lopes Rocha, MD, MSc, PhD

Brief Report

Concurrent SSRI, SNRI, or Other Antidepressant Use Not Associated With Differential Outcomes in Ketamine or Esketamine Treatment

J Clin Psychiatry 2026;87(2):25br16294

Erin Curran, BA; Morgan Hardy, MD, MPH; Rachel Katz, MD; Taeho Greg Rhee, PhD, FACE; Samuel T. Wilkinson, MD

Case Report

$Oral Glutamatergic Modulation With Dextromethorphan and Piracetam for Refractory Bipolar Disorder With Obsessive-Compulsive Disorder: Three Consecutive Cases From Routine Practice$

Case Report

Oral Glutamatergic Modulation With Dextromethorphan and Piracetam for Refractory Bipolar Disorder With Obsessive-Compulsive Disorder: Three Consecutive Cases From Routine Practice

J Clin Psychiatry 2026;87(2):25cr16262

Ngo Cheung, MBBS(HK), FHKAM (Psychiatry)

Letter to the Editor

Metformin for the Prevention of Antipsychotic-Induced Weight Gain: The Optimal Strategy

J Clin Psychiatry. 2026;87(2):25lr16260b

Charles Lung-Cheng Huang, MD, PhD

Letter to the Editor

Neural Dysconnectivity and Affective Disorders: Integrating Sleep and Emotional Regulation Perspectives

J Clin Psychiatry 2026;87(2):26lr16326

Andressa Ferruzzi; Tathiana A. Alvarenga, PhD; José Carlos F. Galduróz, MD,PhD; Adriano Ferruzzi, MSc; Sergio Tufik, MD, PhD; Monica Levy Andersen, PhD

Letter to the Editor

Triple Network Dysconnectivity and Sleep Disturbance in Young People With Suicidal Ideation: Reply to Ferruzzi et al

J Clin Psychiatry 2026;87(2):26lr16326a

Li-Kai Cheng, PhD; Wei-Sheng Huang, MD; Mu-Hong Chen, MD, PhD

Concurrent Metformin and Second-Generation Antipsychotics: The Need to Add Vitamin B<sub>12</sub>

Letter to the Editor

Concurrent Metformin and Second-Generation Antipsychotics: The Need to Add Vitamin B₁₂

J Clin Psychiatry 2026;87(2):25lr16260

Louise S. Mulsant, BASc, RD; M. Omair Husain, MBBS; Benoit H. Mulsant, MD, MS

Vitamin B<sub>12</sub> Deficiency Risk During Metformin Treatment for Weight Management in Second-Generation Antipsychotic Recipients: Reply to Mulsant et al

Letter to the Editor

Vitamin B₁₂ Deficiency Risk During Metformin Treatment for Weight Management in Second-Generation Antipsychotic Recipients: Reply to Mulsant et al

J Clin Psychiatry 2026;87(2):25lr16260a

Jerusha Daggolu, MD; Hua Chen, MD, PhD

Correction

Correction. The Efficacy of Olanzapine/Samidorphan on Negative Symptoms: A Post Hoc Analysis of 56-Week Treatment in Patients With Schizophrenia

J Clin Psychiatry 2026;87(2):26lcx16443

Volume 87 • 2026 • 2

Meta-Analysis

Placebo Effects in Alcohol, Cocaine, and Methamphetamine Use Disorder: A Systematic Review and Meta-Analysis

Narrative Review

Measuring What Matters: Further Validation for the Tardive Dyskinesia Impact Scale, a Novel Patient-Reported Outcome Measure in Valbenazine Clinical Trials

Systematic Review

Thirty Years of the Diagnostic Criteria for Psychosomatic Research (DCPR): A Systematic Review and Discussion of Clinical Implications

Original Research

Using Natural Language Processing to Evaluate Differences in Psychotherapeutic Services for Posttraumatic Stress Disorder in a Suicide-Risk-Stratified Veteran Sample

Nonsuicidal Self-Injury and Its Association With Suicidal Ideation and Negative Affect: A 12-Month Ecological Momentary Assessment

Suicide Risk and Veterans Health Administration Utilization Among Those With a Documented Suicide Attempt in the US Military

A Phase 2b Multicenter Study to Evaluate Basmisanil as an Adjunctive Treatment in Patients With Cognitive Impairment Associated With Schizophrenia

Cognitive Behavioral Therapy Following Esketamine for Major Depression and Suicidal Ideation for Relapse Prevention: The CBT-ENDURE Randomized Trial

Effects of Experimental Intermittent Theta Burst Stimulation on Negative Symptoms of Schizophrenia: A Double-Blind Sham-Controlled Study

Aripiprazole Once-Monthly for Patients Diagnosed With Schizophrenia: Number Needed to Treat, Number Needed to Harm, and Likelihood to be Helped or Harmed

Efficacy and Safety of a Single Dose of Psilocybin for Chronic Suicidal Ideation: An Open-Label Trial

Differential Impact of Cholecystokinin and Ghrelin on 2-Year Avoidant/Restrictive Food Intake Disorder Symptoms

Viloxazine Extended Release in Adults With Attention-Deficit/Hyperactivity Disorder and Depression and/or Anxiety Symptoms: Results From a Decentralized, Open-Label, Phase 4 Trial

Outcomes and Practice Patterns of Long-Acting Injectable Versus Oral Antipsychotics Among Patients With Bipolar I Disorder in the United States: A Hospital Database Analysis

Comparing Risk Prediction for Suicide Attempts and Deaths After Emergency Department Visits for Individuals With Mental Health Disorders

Safety and Efficacy of Maintenance Treatment With Aripiprazole Once-Monthly in Black/African American Adults Diagnosed With Bipolar I Disorder: Post Hoc Analysis of a 52-Week, Open-Label Study

The Efficacy of Olanzapine/Samidorphan on Negative Symptoms: A Post Hoc Analysis of 56-Week Treatment in Patients With Schizophrenia

Temporal Dynamics of Antidepressant Response Following Brexanolone Treatment in Postpartum Depression

Neuropsychiatric Symptom Clusters and Their Association With Brain Structure in Alzheimer Disease

Postmarketing Safety of Transcranial Magnetic Stimulation: A 10-Year MAUDE Database Analysis of Adverse Events and Technological Advancements

Correlates and Predictors of Criminal Legal Involvement in People With First-Episode Psychosis

Commentary

The Patient Perspective on Tardive Dyskinesia

Mind-Body Integration and East-West Fusion for Modern Medicine: Insights From the Diagnostic Criteria for Psychosomatic Research

Biography Inscribed in Biology: The Diagnostic Criteria for Psychosomatic Research and the Embodiment of Lived Experience

The Demoralization Construct in Clinical Practice and Research

Clinical and Practical Psychopharmacology

Proton Pump Inhibitors and the Risk of Dementia

Insomnia, Sleep, and the Use of Sedative-Hypnotic Drugs: Practical Notes

Association of Selective Serotonin Reuptake Inhibitor and Other Antidepressant Drugs With Dental Implant Failure

ASCP Corner

Life After Clozapine: Managing Treatment-Resistant Schizophrenia When Clozapine Is No Longer an Option

Brief Report

Inconsistent MAOI Dietary Guidance From Major AI Chatbots: A Brief Clinical Evaluation

Concurrent SSRI, SNRI, or Other Antidepressant Use Not Associated With Differential Outcomes in Ketamine or Esketamine Treatment

Case Report

Oral Glutamatergic Modulation With Dextromethorphan and Piracetam for Refractory Bipolar Disorder With Obsessive-Compulsive Disorder: Three Consecutive Cases From Routine Practice

Letter to the Editor

Metformin for the Prevention of Antipsychotic-Induced Weight Gain: The Optimal Strategy

Neural Dysconnectivity and Affective Disorders: Integrating Sleep and Emotional Regulation Perspectives

Triple Network Dysconnectivity and Sleep Disturbance in Young People With Suicidal Ideation: Reply to Ferruzzi et al

Concurrent Metformin and Second-Generation Antipsychotics: The Need to Add Vitamin B12

Vitamin B12 Deficiency Risk During Metformin Treatment for Weight Management in Second-Generation Antipsychotic Recipients: Reply to Mulsant et al

Correction

Correction. The Efficacy of Olanzapine/Samidorphan on Negative Symptoms: A Post Hoc Analysis of 56-Week Treatment in Patients With Schizophrenia

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Concurrent Metformin and Second-Generation Antipsychotics: The Need to Add Vitamin B₁₂

Vitamin B₁₂ Deficiency Risk During Metformin Treatment for Weight Management in Second-Generation Antipsychotic Recipients: Reply to Mulsant et al

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